INSIG1 antibody

Principal name

INSIG1 antibody

Alternative names for INSIG1 antibody

INSIG-1, Insulin-induced gene 1 protein

SwissProt ID

A0JNC3 (Bovin), O15503 (Human), Q08755 (Rat), Q5ZMT9 (Chick), Q6DF80 (Xenla)

Gene ID

3638 (INSIG1), 64194 (Insig1)

Available reactivities

Hu (Human), Bov (Bovine), Hst (Hamster), Ms (Mouse), Rt (Rat), Can (Canine), Chk (Chicken), Por (Porcine), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit), Sh (Sheep)

Available hosts

Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C)

Background of INSIG1 antibody

Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

General readings

Roth,A., (2008) Mol. Pharmacol. 73 (4), 1282-1289

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

INSIG1 antibody

Detection of Insig 1 in HepG2 lyaste Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

INSIG1 antibody

Western blot analysis of InSig1 expression in Jurkat cell lysate. Rabbit Purified Bov, Hst, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

INSIG1 antibody

WB Suggested Anti-INSIG1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Spleen Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Sh, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

INSIG1 antibody

WB Suggested Anti-INSIG1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human brain Rabbit IgG Purified Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

INSIG1 antibody

INSIG1 Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

INSIG1 antibody

Western blot analysis of Insig1 expression in Jurkat cell lysate. Rabbit Bov, Hst, Hu, Ms, Rt WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

INSIG1 antibody

Western blot analysis of INSIG1 in HepG2 lyaste using INSIG1 polyclonal antibody ( Cat # PAB12411 ). Rabbit Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

INSIG1 antibody

Human Liver; Immunohistochemistry with Liver tissue at an antibody concentration of 10ug/ml using anti-INSIG1 antibody (ARP40159_P050); INSIG1 antibody - middle region (ARP40159_P050) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

INSIG1 antibody

Human Brain; WB Suggested Anti-INSIG1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human brain; INSIG1 antibody - middle region (ARP40161_P050) in Human Brain cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

INSIG1 antibody

Human Lung; WB Suggested Anti-INSIG1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Lung; INSIG1 antibody - middle region (ARP40162_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

INSIG1 antibody

Human 721_B; Host: Rabbit. Target Name: WT1 . Sample Tissue: 721_B . Antibody Dilution: 1.0ug/ml. INSIG2 is supported by BioGPS gene expression data to be expressed in 721_B.; INSIG1 antibody - middle region (ARP40166_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

INSIG1 antibody

INSIG1 Rabbit Biotin Hu WB
0.1 ml / €360.00
  Novus Biologicals Inc.

INSIG1 antibody

INSIG1 Rabbit DyLight488 Hu WB
0.1 ml / €390.00
  Novus Biologicals Inc.

INSIG1 antibody

INSIG1 Rabbit HRP Hu WB
0.1 ml / €380.00
  Novus Biologicals Inc.

INSIG1 antibody

INSIG1 Rabbit Aff - Purified Hu ICC/IF, WB
25 µl / €200.00
  Novus Biologicals Inc.

15 Item(s)

per page
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