INSIG1 antibody
Principal name
INSIG1 antibody
Alternative names for INSIG1 antibody
INSIG-1, Insulin-induced gene 1 protein
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of INSIG1 antibody
Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
General readings
Roth,A., (2008) Mol. Pharmacol. 73 (4), 1282-1289
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA301693 | INSIG1 antibody |
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| Rabbit Polyclonal Antibody against Insig1 | |||||||
 |
Rabbit | IgG | Purified | Hu | WB |
0.1 ml /
€451.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA318983 | INSIG1 antibody |
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| Rabbit polyclonal anti-Insig1 antibody | |||||||
 |
Rabbit | Purified | Bov, Hst, Hu, Ms, Rt | WB |
0.1 mg /
€388.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA345657 | INSIG1 antibody |
||||||
| Rabbit Polyclonal Anti-INSIG1 Antibody | |||||||
 |
Rabbit | IgG | Purified | Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Sh, Ze | P, WB |
50 µg /
€360.00
|
|
| OriGene Technologies, Inc. | |||||||
 +2 additional images |
|||||||
| TA345658 | INSIG1 antibody |
||||||
| Rabbit Polyclonal Anti-INSIG1 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms | WB |
50 µg /
€360.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA345659 | INSIG1 antibody |
||||||
| Rabbit Polyclonal Anti-INSIG1 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu | WB |
50 µg /
€360.00
|
|
| OriGene Technologies, Inc. | |||||||
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC200312L2V | Lenti ORF particles, INSIG1 (mGFP-tagged) - Human insulin induced gene 1 (INSIG1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€989.00
|
|
| OriGene Technologies, Inc. | ||
| RC223272L2V | Lenti ORF particles, INSIG1 (mGFP-tagged) - Human insulin induced gene 1 (INSIG1), transcript variant 3, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€907.00
|
|
| OriGene Technologies, Inc. | ||
| RC200312L1V | Lenti ORF particles, INSIG1 (Myc-DDK tagged) - Human insulin induced gene 1 (INSIG1), transcript variant 1 , 200 uL, >10^7 TU/mL |
|
|
200 µl /
€886.00
|
|
| OriGene Technologies, Inc. | ||
| RC223272L1V | Lenti ORF particles, INSIG1 (Myc-DDK tagged) - Human insulin induced gene 1 (INSIG1), transcript variant 3 , 200 uL, >10^7 TU/mL |
|
|
200 µl /
€804.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR206261L2V | Lenti ORF particles, Insig1 (GFP-tagged ORF) - Rat insulin induced gene 1 (Insig1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€907.00
|
|
| OriGene Technologies, Inc. | ||
| RR206261L1V | Lenti ORF particles, Insig1 (Myc-DDK-tagged ORF) - Rat insulin induced gene 1 (Insig1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€804.00
|
|
| OriGene Technologies, Inc. | ||
