INSM1 / IA1 antibody

Principal name

INSM1 / IA1 antibody

Alternative names for INSM1 / IA1 antibody

Insulinoma-associated protein 1, Zinc finger protein IA-1

SwissProt ID

A6H7J1 (Bovin), Q01101 (Human), Q63ZV0 (Mouse)

Gene ID

3642 (INSM1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), Por (Porcine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of INSM1 / IA1 antibody

IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.

General readings

Breslin,M.B., et al., (2003) J. Biol. Chem. 278 (40), 38991-38997

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

INSM1 / IA1 antibody

Western blot analysis of IA-1 in rat thymus tissue lysate with IA-1 antibody at 1 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

INSM1 / IA1 antibody

WB Suggested Anti-INSM1 Antibody Titration: 1.25ug/ml; Positive Control: Human Cerebellum Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

INSM1 / IA1 antibody

WB Suggested Anti-INSM1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, Hu, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

INSM1 / IA1 Control Peptide

INSM1 / IA1
50 µg / €160.00
  Acris Antibodies GmbH

INSM1 / IA1 antibody

Human Heart; INSM1 antibody - middle region (ARP31990_T100) in Human Heart cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

INSM1 / IA1 antibody

Human Lung; WB Suggested Anti-INSM1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Lung; INSM1 antibody - C-terminal region (ARP32667_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

INSM1 / IA1 antibody

Western Blot: INSM1 Antibody [NBP1-76307] - Analysis of IA-1 in rat thymus tissue lysate with IA-1 antibody at 1 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

INSM1 / IA1

INSM1 / IA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates (Overexpressed)

Catalog No.    

INSM1 overexpression lysate

INSM1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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