InsP6 kinase 1 / IP6K1 antibody

Principal name

InsP6 kinase 1 / IP6K1 antibody

Alternative names for InsP6 kinase 1 / IP6K1 antibody

IHPK1, KIAA0263, Inositol hexaphosphate kinase 1, Inositol hexakisphosphate kinase 1

SwissProt ID

Q6PD10 (Mouse), Q92551 (Human), Q9ESM0 (Rat)

Gene ID

50560 (Ip6k1), 9807 (IP6K1), 1467752 (Q9Z6M6)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of InsP6 kinase 1 / IP6K1 antibody

Inositol 1,4,5-trisphosphate (IP3) is a second messenger for many growth factors, hormones, and neurotransmitters and, upon binding to the IP3 receptor (IP3R), triggers the release of intracellular, luminal calcium to the cytosol. Several additional cellular forms of inositol phosphates have been discovered. These include some which have been recently discovered and characterized to possess up to seven or eight phosphate groups, including pyrophosphates (PP-IPs: pyrophosphate-inositol phosphates). It has been proposed that high-energy pyrophosphates may participate in protein phosphorylation. Inositol-hexakisphosphate (IP6) kinase, or PiUS (Pi Uptake Stimulator) has ATP synthase activity and transfers a phosphate from PP-IP5 to ADP to form ATP thus suggesting an important physiological role for PP-IP5 and IP6 kinase.

General readings

General / background references:Schell MJ et al. PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase. FEBS Lett 461:169-72 (1999). PubMed PMID: 10567691
Saiardi A et al. Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases. Curr Biol 9:1323-6 (1999). PubMed PMID: 10574768
Huang CF et al. Identification and purification of diphosphoinositol pentakisphosphate kinase, which synthesizes the inositol pyrophosphate bis(diphospho)inositol tetrakisphosphate. Biochemistry 37:14998-5004 (1998). PubMed PMID: 9778378
Voglmaier SM et al. Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor. Proc Natl Acad Sci U S A 93:4305-10 (1996). PubMed PMID: 8633060

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

InsP6 kinase 1 / IP6K1 antibody

IP6K1 antibody detects IP6K1 protein by western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug whole cell lysate/extract of human IHPK1-transfected 293T cells. 10 % SDS-PAGE. IP6K1 antibody (TA308137) dilution: 1:5000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

InsP6 kinase 1 / IP6K1 (N-term) antibody

Western blot analysis of IP6K1 Antibody (N-term) Cat.-No AP52220PU-N in Hela cell line lysates (35ug/lane). This demonstrates the IP6K1 antibody detected the IP6K1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

InsP6 kinase 1 / IP6K1 antibody

InsP6 kinase 1 / IP6K1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

InsP6 kinase 1 / IP6K1 antibody

Western Blot analysis of IP6K1 expression in transfected 293T cell line (H00009807-T01) by IP6K1 MaxPab polyclonal antibody.

Lane 1: IHPK1 transfected lysate(48.51 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

InsP6 kinase 1 / IP6K1 antibody

Western Blot analysis of IP6K1 expression in transfected 293T cell line (H00009807-T01) by IP6K1 MaxPab polyclonal antibody.

Lane 1: IHPK1 transfected lysate(48.51 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

InsP6 kinase 1 / IP6K1 antibody

Western Blot: Inositol Hexakisphosphate Kinase Antibody [NB120-3524] - Figure 1 shows a Western blot of IP6 kinase on rat brain extract using NB120-3524. Rabbit IgG Aff - Purified Rt WB
0.1 mg / €400.00
  Novus Biologicals Inc.

InsP6 kinase 1 / IP6K1 antibody

Immunohistochemistry-Paraffin: IP6K1 Antibody [NBP1-92026] - Immunohistochemical staining of human duodenum shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

InsP6 kinase 1 / IP6K1 (N-term HIS tag, transcript variant 1)

InsP6 kinase 1 / IP6K1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

InsP6 kinase 1 / IP6K1

InsP6 kinase 1 / IP6K1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

InsP6 kinase 1 / IP6K1

InsP6 kinase 1 / IP6K1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

IHPK1 293T Cell Transient Overexpression Lysate(Denatured)

IHPK1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

IP6K1 overexpression lysate

IP6K1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

IP6K1 overexpression lysate

IP6K1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

13 Item(s)

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