InsP6 kinase 1 / IP6K1 antibody

Principal name

InsP6 kinase 1 / IP6K1 antibody

Alternative names for InsP6 kinase 1 / IP6K1 antibody

IHPK1, KIAA0263, Inositol hexaphosphate kinase 1, Inositol hexakisphosphate kinase 1

SwissProt ID

Q6PD10 (Mouse), Q92551 (Human), Q9ESM0 (Rat)

Gene ID

50560 (Ip6k1), 9807 (IP6K1), 1467752 (Q9Z6M6)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of InsP6 kinase 1 / IP6K1 antibody

Inositol 1,4,5-trisphosphate (IP3) is a second messenger for many growth factors, hormones, and neurotransmitters and, upon binding to the IP3 receptor (IP3R), triggers the release of intracellular, luminal calcium to the cytosol. Several additional cellular forms of inositol phosphates have been discovered. These include some which have been recently discovered and characterized to possess up to seven or eight phosphate groups, including pyrophosphates (PP-IPs: pyrophosphate-inositol phosphates). It has been proposed that high-energy pyrophosphates may participate in protein phosphorylation. Inositol-hexakisphosphate (IP6) kinase, or PiUS (Pi Uptake Stimulator) has ATP synthase activity and transfers a phosphate from PP-IP5 to ADP to form ATP thus suggesting an important physiological role for PP-IP5 and IP6 kinase.

General readings

General / background references:Schell MJ et al. PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase. FEBS Lett 461:169-72 (1999). PubMed PMID: 10567691
Saiardi A et al. Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases. Curr Biol 9:1323-6 (1999). PubMed PMID: 10574768
Huang CF et al. Identification and purification of diphosphoinositol pentakisphosphate kinase, which synthesizes the inositol pyrophosphate bis(diphospho)inositol tetrakisphosphate. Biochemistry 37:14998-5004 (1998). PubMed PMID: 9778378
Voglmaier SM et al. Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor. Proc Natl Acad Sci U S A 93:4305-10 (1996). PubMed PMID: 8633060

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

InsP6 kinase 1 / IP6K1 antibody

  Rabbit Polyclonal antibody to IP6K1 (inositol hexakisphosphate kinase 1)  
IP6K1 antibody detects IP6K1 protein by western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug whole cell lysate/extract of human IHPK1-transfected 293T cells. 10 % SDS-PAGE. IP6K1 antibody (TA308137) dilution: 1:5000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

InsP6 kinase 1 / IP6K1 (N-term) antibody

Western blot analysis of IP6K1 Antibody (N-term) Cat.-No AP52220PU-N in Hela cell line lysates (35ug/lane). This demonstrates the IP6K1 antibody detected the IP6K1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

IP6K1 - human gene knockout kit via CRISPR

IP6K1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

IP6K1 - human gene knockout kit via CRISPR

IP6K1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

IP6K1 - human gene knockout kit via CRISPR

IP6K1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

IP6K1 - human gene knockout kit via CRISPR

IP6K1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

InsP6 kinase 1 / IP6K1 (N-term HIS tag, transcript variant 1)

  Purified recombinant protein of Human inositol hexakisphosphate kinase 1 (IP6K1), transcript variant 1, with N-terminal HIS tag, expressed in E.Coli, 50ug  
InsP6 kinase 1 / IP6K1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

IP6K1 overexpression lysate

IP6K1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

IP6K1 overexpression lysate

IP6K1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, IP6K1 (mGFP-tagged)-Human inositol hexakisphosphate kinase 1 (IP6K1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K1 (mGFP-tagged)-Human inositol hexakisphosphate kinase 1 (IP6K1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K1 (Myc-DDK-tagged)-Human inositol hexakisphosphate kinase 1 (IP6K1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K1 (Myc-DDK-tagged)-Human inositol hexakisphosphate kinase 1 (IP6K1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

11 Item(s)

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