InsP6 kinase 2 / IP6K2 antibody

Principal name

InsP6 kinase 2 / IP6K2 antibody

Alternative names for InsP6 kinase 2 / IP6K2 antibody

IHPK2, TCCCIA00113, P(i)-uptake stimulator, PiUS, Inositol hexakisphosphate kinase 2

SwissProt ID

Q80V72 (Mouse), Q95221 (Rabit), Q9R0U1 (Rat), Q9UHH9 (Human)

Gene ID

51447 (IP6K2), 59268 (Ip6k2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of InsP6 kinase 2 / IP6K2 antibody

The members of the inositol hexakisphosphate kinase family, IP6K1 and IP6K2, have a high affinity and selectivity for inositol hexakisphosphate (InsP6) as a substrate. IP6K1 and IP6K2 (also designated PiUS) convert InsP6 to PP-InsP5. However, neither kinase demonstrates any catalytic activity with other inositol pyrophosphates. The presence of InsP6, which inhibits serine/threonine protein phosphatases, increases the influx of calcium across the plasma membrane and implies that it may mediate the regulation of insulin exocytosis. IP6K1 was purified as a 54 kDa protein in rat brain extracts. By homology, IP6K1 and IP6K2 were characterized in mouse as a 50 kDa and 49 kDa protein, respectively. IP6K1 displays ATP synthase activity by transferring a phosphate from PP-InsP5 to ADP, which suggests a role for the IP6 kinases as high energy phosphate donors.

General readings

Fairfax BP.,et al. (2012) Nat. Genet. 44 (5), 502-510

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

InsP6 kinase 2 / IP6K2 antibody

  Rabbit polyclonal anti-IP6K2 antibody  
Western blot analysis of extracts from HUVEC cells, Jurkat cells and COLO cells, using IP6K2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

InsP6 kinase 2 / IP6K2 antibody

Western blot analysis with extracts from A549 cells using InsP6 kinase 2 / IP6K2 antibody (Cat.-No. AP01285PU-N) (1/500). Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

InsP6 kinase 2 / IP6K2 antibody

Immunofluorescence analysis of COS7 cells, using IP6K2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

InsP6 kinase 2 / IP6K2 antibody

Immunofluorescence analysis of COS7 cells, using IP6K2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

IP6K2 - human gene knockout kit via CRISPR

IP6K2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

IP6K2 - human gene knockout kit via CRISPR

IP6K2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

InsP6 kinase 2 / IP6K2 (transcript variant 1)

  Recombinant protein of human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 1  
InsP6 kinase 2 / IP6K2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

InsP6 kinase 2 / IP6K2 (full length, N-term HIS tag, transcript variant 2)

  Purified recombinant protein of Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
InsP6 kinase 2 / IP6K2 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

InsP6 kinase 2 / IP6K2 (1-426, His-tag)

InsP6 kinase 2 / IP6K2 Human Purified > 85 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

InsP6 kinase 2 / IP6K2 (1-426, His-tag)

InsP6 kinase 2 / IP6K2 Human Purified > 85 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, IP6K2 (mGFP-tagged) - Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (mGFP-tagged) - Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 5, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 5, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 6, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 9, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 9, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 10, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (mGFP-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 10, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K2 (Myc-DDK tagged) - Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (Myc-DDK tagged) - Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K2 (Myc-DDK-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (Myc-DDK-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, IP6K2 (Myc-DDK-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, IP6K2 (Myc-DDK-tagged)-Human inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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