Insulin-like growth factor I / IGF1 antibody

Principal name

Insulin-like growth factor I / IGF1 antibody

Alternative names for Insulin-like growth factor I / IGF1 antibody

IGF-I, Somatomedin-C, Mechano growth factor, MGF, IBP1

SwissProt ID

P05019 (Human), P84775 (Xenla)

Gene ID

3479 (IGF1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit, Sheep, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Radioimmunoassay (R), Western blot / Immunoblot (WB), Functional assay (FN), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Neutralisation (NEUT)

Background of Insulin-like growth factor I / IGF1 antibody

The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. IGF-I LR3 is a recombinant analog of human IGF-I comprised of the complete IGF-I sequence, with an Arginine substitution for the third position Glutamic acid, and a 13 amino acid length N terminus peptide extension. Specifically engineered for higher biological potency in vitro, IGF-I LR3 has an increased half-life and a binding aversion to native proteins within the body that make it ideal for both research and large-scale culturing.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Insulin-like growth factor I / IGF1 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-IGF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805748) Mouse IgG2a OTI4B12 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 M23 Purified Hu, Ms, Rb, Rt E, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 M23 Purified Hu, Ms, Rb, Rt E, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 M23 Purified Hu, Ms, Rb, Rt E, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 SPM406 Purified Hu, Ms, Rb, Rt F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 SPM406 Purified Hu, Ms, Rb, Rt F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 SPM406 Purified Hu, Ms, Rb, Rt F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

(0.5ug/ml) staining of Human Uterus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 antibody

Western blot analysis of IGF-1 with 50 ng recombinant human IGF-I. Rabbit Purified Hu E, NEUT, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 antibody

Western blot analysis using 250 ng (Lane 1) and 1 ug (Lane 2) recombinant murine IGF-I. Rabbit Purified Ms NEUT, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 antibody

Western blot analysis using recombinant rat IGF-1. Lane 1: 50 ng, Lane 2: 100 ng, Lane 3: 200 ng. Rabbit Purified Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 antibody

This antibody stained formalin-fixed, paraffin-embedded sections of human breast invasive ductal carcinoma.  The recommended concentration is 0.25 ug/ml with an overnight incubation at 4C.  An HRP-labeled polymer detection system was used with a DAB chromogen.  Optimal results for these conditions were achieved without antigen retrieval.  Optimal concentrations and conditions may vary. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 antibody

Western blot analysis of extracts of various cell lines, using IGF1 antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 antibody

Western blot analysis of IGF1 expression in Human uterus lysate Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 antibody

Immunohistochemical staining of paraffin-embedded Human lung tissue within the normal limits using anti-IGF1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805792) Mouse IgG1 OTI3A6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG2b AT6F8 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG2b AT6F8 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 M23/ILG1-001 Purified Hu E, R
0.2 mg / €330.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 BM23 Purified Hu C, E, R
0.2 mg / €560.00
  Acris Antibodies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Sheep Purified Hu C, E
1 ml / €430.00
  Acris Antibodies GmbH

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