Insulin-like growth factor I / IGF1 antibody

Principal name

Insulin-like growth factor I / IGF1 antibody

Alternative names for Insulin-like growth factor I / IGF1 antibody

IGF-I, Somatomedin-C, Mechano growth factor, MGF, IBP1

SwissProt ID

P05019 (Human), P84775 (Xenla)

Gene ID

3479 (IGF1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit, Sheep, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Radioimmunoassay (R), Western blot / Immunoblot (WB), Functional assay (FN), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Neutralisation (NEUT)

Background of Insulin-like growth factor I / IGF1 antibody

The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. IGF-I LR3 is a recombinant analog of human IGF-I comprised of the complete IGF-I sequence, with an Arginine substitution for the third position Glutamic acid, and a 13 amino acid length N terminus peptide extension. Specifically engineered for higher biological potency in vitro, IGF-I LR3 has an increased half-life and a binding aversion to native proteins within the body that make it ideal for both research and large-scale culturing.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 SPM406 Purified Hu, Ms, Rb, Rt F, ICC/IF, IP, P, WB
0.2 mg / €410.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 SPM406 Purified Hu, Ms, Rb, Rt F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 SPM406 Purified Hu, Ms, Rb, Rt F, ICC/IF, IP, P, WB
20 µg / €180.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 M23 Purified Hu, Ms, Rb, Rt E, F, ICC/IF, IP, P, WB
0.2 mg / €410.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 M23 Purified Hu, Ms, Rb, Rt E, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1 antibody

Insulin-like growth factor I / IGF1 Mouse IgG1 M23 Purified Hu, Ms, Rb, Rt E, F, ICC/IF, IP, P, WB
20 µg / €180.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1 antibody

  Goat Anti-IGF1 Antibody  
(0.5ug/ml) staining of Human Uterus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt E, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 antibody

  Rabbit polyclonal anti-Anti-Rat IGF-1 antibody  
Western blot analysis using recombinant rat IGF-1. Lane 1: 50 ng, Lane 2: 100 ng, Lane 3: 200 ng. Rabbit Purified Rt WB
0.1 mg / €353.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 antibody

  Rabbit Polyclonal Anti-IGF1 antibody  
Western blot analysis of IGF1 expression in Human uterus lysate Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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