Insulin-like growth factor I / IGF1 antibody

Principal name

Insulin-like growth factor I / IGF1 antibody

Alternative names for Insulin-like growth factor I / IGF1 antibody

IGF-I, Somatomedin-C, Mechano growth factor, MGF, IBP1

SwissProt ID

P05019 (Human), P84775 (Xenla)

Gene ID

3479 (IGF1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit, Sheep, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Radioimmunoassay (R), Western blot / Immunoblot (WB), Functional assay (FN), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Neutralisation (NEUT)

Background of Insulin-like growth factor I / IGF1 antibody

The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. IGF-I LR3 is a recombinant analog of human IGF-I comprised of the complete IGF-I sequence, with an Arginine substitution for the third position Glutamic acid, and a 13 amino acid length N terminus peptide extension. Specifically engineered for higher biological potency in vitro, IGF-I LR3 has an increased half-life and a binding aversion to native proteins within the body that make it ideal for both research and large-scale culturing.

9 Item(s)

per page

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Insulin-like growth factor I / IGF1 (Long R3)

Insulin-like growth factor I / IGF1 (Long R3) Human Purified > 98 % pure by SDS-PAGE and HPLC analyses E. coli
1 mg / €220.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1 (Long R3)

Insulin-like growth factor I / IGF1 (Long R3) Human Purified > 98 % pure by SDS-PAGE and HPLC analyses E. coli
0.2 mg / €140.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1 (transcript variant 4)

  Recombinant protein of human insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 4  
Insulin-like growth factor I / IGF1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 (transcript variant 4)

  Recombinant protein of human insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 4  
Insulin-like growth factor I / IGF1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1 (transcript variant 4)

  Purified recombinant protein of Human insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 4.  
Insulin-like growth factor I / IGF1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
0.1 mg / €139.00
  OriGene Technologies, Inc.

Insulin-like growth factor I / IGF1

Insulin-like growth factor I / IGF1 Human Purified > 95 % pure by SDS-PAGE E. coli
0.5 mg / €540.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1

Insulin-like growth factor I / IGF1 Human Purified > 95 % pure by SDS-PAGE E. coli
0.1 mg / €230.00
  OriGene Technologies GmbH

Insulin-like growth factor I / IGF1

Insulin-like growth factor I / IGF1 Human Purified > 97 % E. coli
50 µg / €250.00
  Neuromics Antibodies

Insulin-like growth factor I / IGF1

Insulin-like growth factor I / IGF1 Human Purified > 97 % E. coli
0.25 mg / €640.00
  Neuromics Antibodies

9 Item(s)

per page
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