Insulin-like growth factor II / IGF2 antibody

Principal name

Insulin-like growth factor II / IGF2 antibody

Alternative names for Insulin-like growth factor II / IGF2 antibody

IGF-II, Somatomedin-A

SwissProt ID

P01344 (Human), P01346 (Rat), P07456 (Bovin), P09535 (Mouse), P10764 (Sheep), P23695 (Pig), P33717 (Chick), P51459 (Horse), Q08279 (Cavpo)

Gene ID

3481 (IGF2), 16002 (Igf2), 24483

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Por (Porcine)

Available hosts

Rabbit, Mouse, Rat, Goat

Available applications

Enzyme Immunoassay (E), Functional assay (FN), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of Insulin-like growth factor II / IGF2 antibody

Insulin-like growth factor II (also known as multiplication stimulating activity or MSA) and insulin-like growth factor I (IGF-I) belong to the family of insulin-like growth factors which are structurally homologous to proinsulin. Mature IGF-I and IGF-II are highly conserved and share approx imately 70% amino acid sequence identity. Mouse IGF-II, a 67 amino acid protein, has a predicted molecular mass of approximately 7.4 kDa. Mouse and human IGF-II share 91% sequence identity.
Insulin-like growth factor II has autocrine, paracrine, and endocrine functions. It is a potent mitogenic growth factor that mediates growth-promoting activities in embryonic development. IGF-II binds the IGF-II receptor with high affinity. IGF-I and IGF II are expressed in many tissues and cell types. IGF-II is mitogenic for a variety of cultured cells including human or chicken fibroblasts, mouse 3T3 cells, normal rat kidney cells, and MCF-7 human breast carcinoma cells.

General readings

Pedersen S.K., et al. (2002). Biochem. J. 363: 37-44.

4 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Insulin-like growth factor II / IGF2 antibody

  Rabbit anti-IGF2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using IGF2 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

Insulin-like growth factor II / IGF2 (81-93) antibody

Staining of paraffin embedded Human Cerebellum using IGF2 Antibody Cat.-No AP33296PU-N at 5 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, P
0.1 mg / €350.00
  OriGene Technologies GmbH

Insulin-like growth factor II / IGF2 antibody

Insulin-like growth factor II / IGF2 Rat IgG2 3J42 Purified Hu, Ms WB
0.1 mg / €440.00
  OriGene Technologies GmbH

ELISA Kits

Catalog No.    

Mouse IGF-2 ELISA Kit

Mouse IGF-2 ELISA Kit  
1 kit / €507.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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