Integrin alpha-8 / ITGA8 antibody

Principal name

Integrin alpha-8 / ITGA8 antibody

SwissProt ID

A2ARA8 (Mouse), P26009 (Chick), P53708 (Human)

Gene ID

8516 (ITGA8)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Ms (Mouse), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Integrin alpha-8 / ITGA8 antibody

Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell sigling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with rel hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alterte splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2014].

General readings

Benoit, Y.D., et al. Biochem. Biophys. Res. Commun. 399(3):434-439(2010)
Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009)
Benoit, Y.D., et al. Biol. Cell 101(12):695-708(2009)
Sato, Y., et al. J. Biol. Chem. 284(21):14524-14536(2009)
Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Integrin alpha-8 / ITGA8 antibody

WB Suggested Anti-ITGA8 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Spleen Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Integrin alpha-8 / ITGA8 (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with Integrin alpha-8 / ITGA8 Antibody (C-term) Cat.-No AP52252PU-N, which was peroxidase conjugated to the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Integrin alpha-8 / ITGA8 antibody

Integrin alpha-8 / ITGA8 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Integrin alpha-8 / ITGA8 antibody

Integrin alpha-8 / ITGA8 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Integrin alpha-8 / ITGA8 antibody

Integrin alpha-8 / ITGA8 Mouse IgG2b 2G7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Integrin alpha-8 / ITGA8 antibody

Human Spleen; WB Suggested Anti-ITGA8 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Spleen; ITGA8 antibody - N-terminal region (ARP45491_P050) in Human Spleen cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Integrin alpha-8 / ITGA8 antibody

Western Blot: ITGA8 Antibody [NBP1-59940] - This Anti-ITGA8 antibody was used in Western Blot of Fetal Spleen    tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Integrin alpha-8 / ITGA8 antibody

Immunohistochemistry-Paraffin: ITGA8 Antibody [NBP1-86519] - Immunohistochemistry-Paraffin: ITGA8 Antibody [NBP1-86519] Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in glomeruli. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Integrin alpha-8 / ITGA8

Integrin alpha-8 / ITGA8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Integrin alpha-8 / ITGA8

Integrin alpha-8 / ITGA8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Integrin alpha-8 / ITGA8

Integrin alpha-8 / ITGA8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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