Integrin beta-5 / ITGB5 antibody

Principal name

Integrin beta-5 / ITGB5 antibody

Alternative names for Integrin beta-5 / ITGB5 antibody

ITGB-5

SwissProt ID

O70309 (Mouse), P18084 (Human), P80747 (Bovin), Q07441 (Papcy)

Gene ID

3693 (ITGB5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Hst (Hamster), Chk (Chicken), Bov (Bovine), Can (Canine), Por (Porcine), Mky (Monkey), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair)

Background of Integrin beta-5 / ITGB5 antibody

Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer. This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated. This integrin is found in a variety of cells in most normal tissue.

General readings

1. Becker L  et al. Unique proteomic signatures distinguish macrophages and dendritic cells.PLoS One 7:e33297 (2012). ICC/IF ; Mouse .PubMed: 22428014
2. Miranda A  et al. Prion protein expression regulates embryonic stem cell pluripotency and differentiation. PLoS One 6:e18422 (2011).PubMed: 21483752

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Integrin beta-5 / ITGB5 antibody

Western blot analysis of ITGB5 over-expressed 293 cell line, cotransfected with ITGB5 Validated Chimera RNAi ( Cat # H00003693-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with ITGB5 monoclonal antibody (M01), clone 2C4 (Cat # H00003693-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG1 2C4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Integrin beta-5 / ITGB5 (C-term) antibody

Human small intestine stained with Anti-Integrin beta 5 antibody Rabbit Purified Hst, Hu, Ms, Rt ICC/IF, IP, P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

Integrin beta-5 / ITGB5 antibody

Human small intestine stained with Anti-Integrin beta 5 antibody Rabbit Purified Hst, Hu, Ms, Rt ICC/IF, IP, P, WB
1 ml / €520.00
  Acris Antibodies GmbH

Integrin beta-5 / ITGB5 (C-term) antibody

Human small intestine stained with Anti-Integrin beta 5 antibody Rabbit Purified Hst, Hu, Ms, Rt P
0.1 ml / €190.00
  Acris Antibodies GmbH

Integrin beta-5 / ITGB5 antibody

Western blot analysis of extracts from COS7 cells, using Integrin Ã?5 antibody (#TA311660).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Integrin beta-5 / ITGB5 antibody

Western blot analysis of extracts of various cell lines, using ITGB5 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Integrin beta-5 / ITGB5 antibody

Western blot analysis on COS7 cell lysate using Integrin beta-5 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Integrin beta-5 / ITGB5 antibody

Western blot (WB) analysis of Integrin ?5 antibody (Cat.-No.: AP06183PU-N) at 1/500 dilution Lane1:Hela whole cell lysate Lane2:HEK293T whole cell lysate Lane3:Raw264.7 whole cell lysate Lane4:Rat kidney tissue lysate Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Integrin beta-5 / ITGB5 antibody

Integrin beta-5 / ITGB5 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Integrin beta-5 / ITGB5 antibody

ITGB5 MaxPab rabbit polyclonal antibody. Western Blot analysis of ITGB5 expression in mouse kidney. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Integrin beta-5 / ITGB5 antibody

Integrin beta-5 / ITGB5 Mouse IgG1 1D8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Integrin beta-5 / ITGB5 antibody

Integrin beta-5 / ITGB5 Goat Hu, Ms E
0.1 mg / €400.00
  Abnova Taiwan Corp.

Integrin beta-5 / ITGB5 antibody

Immunohistochemical staining of ITGB5 on formalin fixed, paraffin embedded human small intestine with ITGB5 polyclonal antibody. Rabbit Hu ICC/IF, IP, P, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Integrin beta-5 / ITGB5 antibody

Western blot analysis of extracts from COS7 cells, using Integrin beta5 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Integrin beta-5 / ITGB5 antibody

Western blot analysis of extracts from COS7 cells, using Integrin beta5 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

Integrin beta-5 / ITGB5 antibody

Human Spleen; WB Suggested Anti-ITGB5 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Spleen; ITGB5 antibody - middle region (ARP45247_P050) in Human Spleen cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Integrin beta-5 / ITGB5 antibody

Western blot analysis of Integrin beta 5 expression in HeLa (A); SW480 (B); HT29 (C); A549 (D); Raw264.7 (E); rat kidney (F) whole cell lysates. Rabbit Aff - Purified Bov, Can, Hu, Mky, Ms, Por, Rb, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Integrin beta-5 / ITGB5 antibody

Western blot analysis of Integrin beta 5 expression in HeLa (A); SW480 (B); HT29 (C); A549 (D); Raw264.7 (E); rat kidney (F) whole cell lysates. Rabbit Aff - Purified Bov, Can, Hu, Mky, Ms, Por, Rb, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Integrin beta-5 / ITGB5 antibody

Western blot analysis of Integrin beta 5 expression in HeLa (A); SW480 (B); HT29 (C); A549 (D); Raw264.7 (E); rat kidney (F) whole cell lysates. Rabbit Aff - Purified Bov, Can, Hu, Mky, Ms, Por, Rb, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Integrin beta-5 / ITGB5 antibody

Integrin beta-5 / ITGB5 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

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