Interleukin-22 / IL22 antibody

Principal name

Interleukin-22 / IL22 antibody

Alternative names for Interleukin-22 / IL22 antibody

IL-22, ILTIF, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor

SwissProt ID

Q9GZX6 (Human), Q9JJY9 (Mouse)

Gene ID

50929 (Il22), 50616 (IL22)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit), Sh (Sheep)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Interleukin-22 / IL22 antibody

IL-22 is an inflammatory cytokine produced by so-called Th22 cells, especially, as well as Th17 cells. Activating through STAT3 sigling cascades, IL-22 is also expressed by numerous types of lymphocytes including LTi and LTi-like cells in the gut, Nk and T cells, and Langerhans cells which are APCs in the skin (1, 2). The protein is therefore expressed in effector cells of both the Inte and Adaptive Immune systems. Th22 cells, a subset of CD4 cells, preferentially express IL-22 and also express CCR6, CCR4 and CCR10--the latter two representing skin-homing receptors (3-5). Th22 cells do not express RORt or T-bet IL-17A or IFN (4). However, AHR appears to be a key priming transcription element for IL-22 as for IL-17A expression (5). IL-6 and TNF induce Th22 priming (1, 5). It also appears to have positive activities in wound healing and tissue repair since deficiencies in IL-22 in mouse models delay healing of intestil biopsies (6). Other tissue repair activities have also been identified with the protein. Taken together, IL-22 is thought to be a key to maintaining a balance between inflammation and tolerance, or homeostasis, especially in skin and mucosal organs like the gut.

General readings

Aujla,S.J., (2008) Nat. Med. 14 (3), 275-281

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Interleukin-22 / IL22 antibody

Western blot analysis of IL-22 in HeLa cell lysate with IL-22 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Interleukin-22 / IL22 antibody

To detect hIL-22 by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human IL-22 as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hIL-22. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Interleukin-22 / IL22 antibody

To detect mIL-22 by direct ELISA (using 100 ul/well antibody solution) a concentration of 0.25-1.0 ug/ml of this antibody is required.  This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2-0.4 ng/well of recombinant mIL-22. Rabbit IgG Purified E, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Interleukin-22 / IL22 antibody

To detect mIL-22 by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Murine IL-22 (TA328506) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mIL-22. Rabbit IgG Purified E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Interleukin-22 / IL22 antibody

Western Blot: IL22 Antibody (8F11E2) [TA337159] - analysis of IL-22 in A) recombinant protein and B) human spleen lysate using IL-22 antibody at 1 ug/ml. I goat anti-mouse Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this te Mouse 8F11E2 Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Interleukin-22 / IL22 antibody

WB Suggested Anti-IL22 Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Rabbit Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Rabbit Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Rabbit Aff - Purified Hu E, WB
50 µg / €220.00
  Acris Antibodies GmbH

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Rabbit Biotin Ms E, WB
25 µg / €230.00
  Acris Antibodies GmbH

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Rabbit Biotin Ms E, WB
50 µg / €340.00
  Acris Antibodies GmbH

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Rabbit Aff - Purified Ms E, WB
50 µg / €230.00
  Acris Antibodies GmbH

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Rabbit Aff - Purified Ms E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Interleukin-22 / IL22 antibody

Interleukin-22 / IL22 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Interleukin-22 / IL22 antibody

Human HeLa; WB Suggested Anti-IL22 Antibody Titration: 0.2-1 ug/ml. Positive Control: Hela cell lysate; IL22 antibody - C-terminal region (ARP49523_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Interleukin-22 / IL22

Interleukin-22 / IL22 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Interleukin-22 / IL22

Interleukin-22 / IL22 Mouse > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

Interleukin-22 / IL22

Interleukin-22 / IL22 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 10 µg / €199.00

Special Price: 10 µg / €139.00

  OriGene Technologies, Inc.

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