Interleukin-29 / IL29 antibody

Principal name

Interleukin-29 / IL29 antibody

Alternative names for Interleukin-29 / IL29 antibody

Interferon lambda-1, ZCYTO21, IFNL1

SwissProt ID

Q8IU54 (Human)

Gene ID

282618 (IL29)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Neutralisation (NEUT)

Background of Interleukin-29 / IL29 antibody

IL-29 is a protein of the helical cytokine family and is a type III interferon sharing many functions with the type I family of interferons. The IL-29 gene is found on chromosome 19 in humans. It is also known as IFN-lambda1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon. IL-29 does not bind the IFN-alpha/beta receptor, but instead signals through a receptor composed of the IL-28R1 and IL-10R2 subunits. Initial characterizations of the receptor demonstrated that it has a ubiquitous tissue distribution and is expressed on most non-hematopoietic cells. Generation of native IL-29 is achieved by monocytes and dendritic cells in response to viral infection and stimulation with toll-like receptor ligands. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL 29 has significant antiviral activity and immunoregulatory properties and appears to inhibit T helper-2 (Th2) responses regarding inhibition of IL-13 production, compared with IL-4 or IL-5. The antiviral activities of IL-29 include the upregulation of MHC Class I expression on the cell surface and the expression of PKR. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

General readings

Kotenko S.V., et al. (2003) Nat. Immunol, 4:69-77

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Interleukin-29 / IL29 antibody

Anti-human IL-29 antibody in WB shows detection of recombinant human IL-29 raised in E.coli. Recombinant protein (0.1 µg, 19.9 kDa) was loaded onto and resolved by SDS-PAGE, then transferred to nitrocellulose. The membrane was incubated with Rockland's, Inc. Anti-Human IL-29. After washing, membrane was probed with secondary antibody Dylight™ 649 Conjugated Anti-Rabbit IgG (H&L) (Goat) Antibody (611-143-122) diluted 1:20,000. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Interleukin-29 / IL29 antibody

Interleukin-29 / IL29 Mouse IgG2b B-S29 Azide Free Hu E
0.5 mg / €460.00
  Acris Antibodies GmbH

Interleukin-29 / IL29 antibody

Interleukin-29 / IL29 Mouse IgG2a B-Z29 Azide Free Hu E
0.5 mg / €460.00
  Acris Antibodies GmbH

Interleukin-29 / IL29 antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Interleukin-29 / IL29 antibody

Interleukin-29 / IL29 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Interleukin-29 / IL29 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with IL29 polyclonal antibody ( Cat # PAB3666 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Interleukin-29 / IL29

Interleukin-29 / IL29 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

Interleukin-29 / IL29 (20-200, His-tag)

Interleukin-29 / IL29 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Interleukin-29 / IL29 (20-200, His-tag)

Interleukin-29 / IL29 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Interleukin-29 / IL29

Interleukin-29 / IL29 Human ≥ 98 pure by SDS-PAGE and HPLC analyses. E. coli
5 µg / €140.00
  Acris Antibodies GmbH

Interleukin-29 / IL29

Interleukin-29 / IL29 Human ≥ 98 pure by SDS-PAGE and HPLC analyses. E. coli
20 µg / €230.00
  Acris Antibodies GmbH

Interleukin-29 / IL29

Interleukin-29 / IL29 Human
20 µg / €290.00
  Abnova Taiwan Corp.

Interleukin-29 / IL29

Interleukin-29 / IL29 Human
20 µg / €290.00
  Abnova Taiwan Corp.

Interleukin-29 / IL29 (Carrier Free)

Interleukin-29 / IL29 Human Purified > 95 % Mouse
25 µg / €480.00
  PBL Assay Science

ELISA Kits

Catalog No.    

Human IL-29 ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

IL29 (Human) ELISA Kit

IL29 (Human) ELISA Kit  
1 kit / €590.00
  Abnova Taiwan Corp.

IL29 ELISA Kit

IL29 ELISA Kit  
96 Tests / €620.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

IFNL1 overexpression lysate

IFNL1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

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