Intersectin-1 / ITSN1 antibody

Principal name

Intersectin-1 / ITSN1 antibody

Alternative names for Intersectin-1 / ITSN1 antibody

ITSN, SH3D1A, SH3P17, SH3 domain-containing protein 1A

SwissProt ID

O42287 (Xenla), Q15811 (Human), Q9WVE9 (Rat), Q9Z0R4 (Mouse)

Gene ID

6453 (ITSN1), 5236453 (accD)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Ms (Mouse), Rb (Rabbit), Rt (Rat)

Available hosts

Chicken, Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of Intersectin-1 / ITSN1 antibody

Intersectin 1 is an adapter protein that may provide an indirect link between the endocytic membrane traffic and the actin assembly machinery. It may regulate the formation of clathrin-coated vesicles. Isoform 1 could be involved in brain-specific synaptic vesicle recycling. Intersectin 1 is overexpressed in brain from Down syndrome foetuses suggesting a gene dosage-dependent contribution to the abnormalities of Down syndrome. Intersectin 1 interacts with dynamin, CDC42, SNAP25 and SNAP23. It clusters several dynamin in a manner that is regulated by alternative splicing. Intersectin 1 also binds clathrin-associated proteins and other components of the endocytic machinery, such as SPIN90, EPS15, EPN1, EPN2 and STN2. Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Isoform 1 could be involved in brain-specific synaptic vesicle recycling.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Intersectin-1 / ITSN1 antibody

Host: Rabbit; Target Name: Itsn1; Sample Tissue: Mouse Thymus lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Intersectin-1 / ITSN1 antibody

Intersectin-1 / ITSN1 Mouse IgG2b 2F12 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Intersectin-1 / ITSN1 antibody

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-ITSN1) Chicken Aff - Purified Hu WB
50 µg / €520.00
  Novus Biologicals Inc.

Intersectin-1 / ITSN1 antibody

Immunopreciptationt: Intersectin 1 Antibody [NBP1-71832] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells.  _x000d_
Antibodies:  Affinity purified rabbit anti-Intersectin 1 antibodyNBP1-71832 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate.  Intersectin 1 was also immunoprecipitated by rabbit anti-Intersectin 1 antibody BL11132, which recognizes an upstream epitope. Rabbit IgG Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Intersectin-1 / ITSN1 antibody

Immunohistochemistry-Paraffin: Intersectin 1 Antibody [NBP1-87806] - Immunohistochemical staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Intersectin-1 / ITSN1

Intersectin-1 / ITSN1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Intersectin-1 / ITSN1

Intersectin-1 / ITSN1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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