INTS3 antibody

Principal name

INTS3 antibody

Alternative names for INTS3 antibody

Integrator complex subunit 3, C1orf193, C1orf60, FLJ21919, INT3

SwissProt ID

Q68E01 (Human), Q7TPD0 (Mouse)

Gene ID

65123 (INTS3)

Ncbi ID

9606, NP_075391

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of INTS3 antibody

RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. INTS3 (integrator complex subunit 3), also known as INT3 or SOSS-A, is a 1,043 amino acid nuclear protein and is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1 and U2. Expressed in the nucleus, INTS3 exists as four alternatively spliced isoforms and is encoded by a gene located on human chromosome 1q21.3.

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Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

INTS3

INTS3 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

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