IQSEC1 antibody

Principal name

IQSEC1 antibody

Alternative names for IQSEC1 antibody

ARFGEP100, BRAG2, KIAA0763, IQ motif and SEC7 domain-containing protein 1, ADP-ribosylation factors guanine nucleotide-exchange protein 100, ADP-ribosylation factors guanine nucleotide-exchange protein 2, Brefeldin-resistant Arf-GEF 2 protein

SwissProt ID

Q6DN90 (Human), Q8R0S2 (Mouse)

Gene ID

9922 (IQSEC1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of IQSEC1 antibody

ADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation. IQSEC1 (GEP100/BRAG2), a guanine nucleotide exchange protein for ARF6, belongs to the BRAG family and contains one IQ domain, one PH domain and one SEC7 domain (1). As a known activator of ARF6, IQSEC1 regulates cell surface levels of Beta1 integrin and its knockdown blocked tumour metastasis (2,3). IQSEC1 links EGFR sigling to ARF6 activation and may contribute to the cancer metastasis and maligncy (4).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IQSEC1 antibody

Western blot analysis of IQSEC1 in A20 cell lysate with IQSEC1 antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  


IQSEC1 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.


Catalog No.    

IQSEC1 overexpression lysate

IQSEC1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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