IRF2 antibody

Principal name

IRF2 antibody

Alternative names for IRF2 antibody

Interferon regulatory factor 2, IRF-2

SwissProt ID

P14316 (Human), P23906 (Mouse), Q98925 (Chick)

Gene ID

3660 (IRF2), 16363 (Irf2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair)

Background of IRF2 antibody

Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3gamma p48 (the 48 kDa component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP).

General readings

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)
Lace, M.J., et al. Virology 399(2):270-279(2010)
Masumi, A., et al. Biochem. Biophys. Res. Commun. 391(4):1623-1628(2010)
Daley, D., et al. Hum. Genet. 125(4):445-459(2009)
Dhar, D., et al. PLoS ONE 4 (9), E7049 (2009)

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IRF2 (C-term) antibody

  Goat Polyclonal Antibody against IRF2  
TA302517 staining (2µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRF2 antibody

  Rabbit polyclonal anti-IRF2 antibody  
Western blot analysis of extracts from Jurkat cells and COLO205 cells, using IRF2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

IRF2 antibody

  Rabbit Polyclonal Anti-IRF2 Antibody  
WB Suggested Anti-IRF2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

IRF2 antibody

  Rabbit Polyclonal Anti-IRF2 Antibody  
WB Suggested Anti-IRF2 Antibody Titration: 5.0ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRF2 antibody

  Mouse Monoclonal anti-IRF2 Antibody  
Total cell lysate from Jurkat cells (lane 1), Ramos cells (lane 2), and mouse splenocytes (lane 3) were resolved by electrophoresis, transferred to nitrocellulose, and probed with purified monoclonal anti-IRF2 (clone 13B2A38) antibody. Proteins were visualized using an anti-mouse-IgG secondary conjugated to HRP and chemiluminescence detection. Mouse 13B2A38 Purified Hu, Ms ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRF2 antibody

Immunohistochemistry (IHC) analyzes of IRF-2 antibody (Cat.-No.: AP06668PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

IRF2 (Center) antibody

Western blot analysis of IRF2 Antibody (Center) Cat.-No AP52235PU-N in mouse bladder tissue lysates (35ug/lane). This demonstrates the IRF2 antibody detected the IRF2 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

IRF2 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using IRF2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

IRF2 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using IRF2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

IRF2 - human gene knockout kit via CRISPR

IRF2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

IRF2 - human gene knockout kit via CRISPR

IRF2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IRF2

  Recombinant protein of human interferon regulatory factor 2 (IRF2)  
IRF2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

IRF2 (full length, C-term DDK tag)

  Recombinant protein of human interferon regulatory factor 2 (IRF2), full length, with C-terminal DDK tag, expressed in sf9, 20ug  
IRF2 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

IRF2 (1-113, His-tag)

IRF2 Human Purified ≥ 95 by SDS PAGE E. coli
0.5 mg / €1,000.00
  Acris Antibodies GmbH

IRF2 (1-113, His-tag)

IRF2 Human Purified ≥ 95 by SDS PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

IRF2 overexpression lysate

IRF2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Irf2 (GFP-tagged) - Mouse interferon regulatory factor 2 (Irf2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Irf2 (GFP-tagged) - Mouse interferon regulatory factor 2 (Irf2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Irf2 (Myc-DDK-tagged) - Mouse interferon regulatory factor 2 (Irf2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Irf2 (Myc-DDK-tagged) - Mouse interferon regulatory factor 2 (Irf2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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