IRF4 antibody

Principal name

IRF4 antibody

Alternative names for IRF4 antibody

Interferon regulatory factor 4, NF-EM5, MUM1, LSIRF, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1

SwissProt ID

Q15306 (Human), Q64287 (Mouse)

Gene ID

3662 (IRF4)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Goat, Rat

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Frozen Sections (C), ELISA (detection) (E(detection))

Background of IRF4 antibody

IRF4 Antibody: Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of inte and adaptive antiviral mechanisms. During infection, host-virus interactions sigl downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. Another member, IRF7 has been shown to play a role in the transcriptiol activation of virus-inducible cellular genes, including interferon beta chain genes. IRF4 expression is tightly regulated in resting primary T cells and plays an essential role in the homeostasis and function of mature lymphocytes. IRF4 is induced by Toll-like receptor (TLR) activation and acts as a negative regulator of TLR sigling.

General readings

General / background references:Natkunam Y et al. Analysis of MUM1/IRF4 protein expression using tissue microarrays and immunohistochemistry. Mod Pathol 14:686-94 (2001). PubMed PMID: 11455001
Falini B et al. A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. Blood 95:2084-92 (2000). PubMed PMID: 10706878
Gaidano G & Carbone A MUM1: a step ahead toward the understanding of lymphoma histogenesis. Leukemia 14:563-6 (2000). PubMed PMID: 10764139

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IRF4 antibody

Human Neutrophils: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 2F2 Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

IRF4 antibody

Human Hodgkin's lymphoma stained with anti-MUM1/IRF4 antibody. Rabbit IgG SP114 Purified Hu P, WB
0.5 ml / €510.00
  Acris Antibodies GmbH

IRF4 antibody

Human Hodgkin's lymphoma stained with anti-MUM1/IRF4 antibody. Rabbit IgG SP114 Purified Hu P, WB
1 ml / €730.00
  Acris Antibodies GmbH

IRF4 antibody

Human Hodgkin's lymphoma stained with anti-MUM1/IRF4 antibody. Rabbit IgG SP114 Purified Hu P, WB
0.1 ml / €290.00
  Acris Antibodies GmbH

IRF4 antibody

AP15668PU IRF4 antibody staining of Human Hodgkin's Lymphoma. Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

IRF4 antibody

AP15668PU IRF4 antibody staining of Human Hodgkin's Lymphoma. Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

IRF4 antibody

AP15668PU IRF4 antibody staining of Human Hodgkin's Lymphoma. Rabbit Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

IRF4 (C-term) antibody

(0.5ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRF4 antibody

Western blot analysis of extracts from HeLa cells and Jurkat cells, using IRF4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

IRF4 (C-term) antibody

Western blot analysis of IRF4 in Jurkat cell lysate with IRF4 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRF4 antibody

Immunohistochemistry staining of Paraffin Tonsil tissue by MUM1 antibody (dilution: 1:100 - 1:500; visualization of staining: Nuclear, cytoplasmic) Rabbit IgG1 MRQ-43 Purified Hu P
1 ml / €240.00
  OriGene Technologies, Inc.

IRF4 (C-term) antibody

Western blot analysis of Daudi (lane 1) , Raji(lane 2) and A20 (lane 3) cells using IRF4 antibody (clone IRF4.3E4). β-actin antibody (poly6221) was used as loading control. Rat IgG1 IRF4.3E4 Purified Hu, Ms F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRF4 antibody

WB Suggested Anti-IRF4 Antibody Titration: 5ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRF4 antibody

WB Suggested Anti-IRF4 Antibody Titration: 5.0 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

IRF4 antibody

Host: Rabbit; Target Name: IRF4; Sample Tissue: Human Fetal Muscle; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Can, Eq, GP, Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

IRF4 antibody

Western blot analysis on HeLa cell lysate using IRF4 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRF4 antibody

IRF4 Mouse IgG1 KBA.62 Supernatant Hu C, P
1 ml / €670.00
  Acris Antibodies GmbH

IRF4 antibody

Western blot (WB) analysis of IRF-4 antibody (Cat.-No. AP01237PU-N) in extracts from HeLa cells. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

IRF4 control peptide

IRF4
50 µg / €160.00
  Acris Antibodies GmbH

IRF4 (Center) antibody

Western blot analysis of IRF4 (arrow) using IRF4 Antibody (Center) Cat.-No AP52236PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the IRF4 gene. Rabbit Ig Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

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