IRGC antibody

Principal name

IRGC antibody

Alternative names for IRGC antibody

IIGP5, IRGC1, Cinema 1, Interferon-inducible GTPase 5, Immunity-related GTPase cinema 1

SwissProt ID

Q32KW9 (Bovin), Q6AYF9 (Rat), Q6NXR0 (Human), Q8C262 (Mouse)

Gene ID

56269 (IRGC), 210145 (Irgc1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of IRGC antibody

Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines. As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans. Two isoforms of IRGC are known to exist; this antibody will only recognize the IRGCa isoform.

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IRGC (N-term) antibody

Western blot analysis of IRGC in A20 cell lysate with IRGC antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRGC (C-term) antibody

Western blot analysis of IRGC in mouse brain tissue lysate with IRGC antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRGC antibody

WB Suggested Anti-Irgc1 Antibody; Titration: 1.0 ug/ml; Positive Control: Mouse Brain Rabbit IgG Purified Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

IRGC (N-term) antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

IRGC Control Peptide

IRGC
50 µg / €160.00
  Acris Antibodies GmbH

IRGC Control Peptide

IRGC
50 µg / €160.00
  Acris Antibodies GmbH

IRGC (N-term) antibody

Mouse Brain; WB Suggested Anti-Irgc1 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Brain; Irgc1 antibody - N-terminal region (ARP57347_P050) in Mouse Brain cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

IRGC antibody

IRGC Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

IRGC antibody

Immunocytochemistry: IRGC Antibody [NBP1-77363] - A20 cells with IRGC antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

IRGC antibody

Immunocytochemistry: IRGC Antibody [NBP1-77364] - A20 cells with IRGC antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IRGC

IRGC Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

IRGC

IRGC Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

IRGC

IRGC Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

13 Item(s)

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