IRX1 / IRXA1 antibody

Principal name

IRX1 / IRXA1 antibody

Alternative names for IRX1 / IRXA1 antibody

Iroquois homeobox protein 1, IRX-1, Iroquois-class homeodomain protein IRX-1, Homeodomain protein IRXA1

SwissProt ID

P78414 (Human), P81068 (Mouse)

Gene ID

79192 (IRX1), 16371 (Irx1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of IRX1 / IRXA1 antibody

The Iroquois homeobox gene family of transcription factors regulate aspects of embryonic development including anterior/posterior and dorsal/ventral axis patterning in the central nervous system. The Iroquois family are clustered on two loci, IRXA and IRXB, which map to chromosomes 8 and 13 in mice. The IRXA group includes Irx1, Irx2 and Irx4; the IRXB group is comprises Irx3, Irx5 and Irx6. Irx1 and Irx2 are both widely expressed during development in the lung epithelium and also in the ventricular septum. Irx1 and Irx2 also play a role in digit formation (E11.5–E14.5). The Irx gene family members are each expressed in a distinct pattern during mouse heart development. Specifically, Irx1 and Irx2 are expressed in the ventricular septum and Irx3 is expressed in the ventricular trabeculated myocardium. In addition, Irx4 is expressed in the linear heart tube and the AV canal; Irx5 is expressed in the endocardium lining the ventricular and atrial myocardium. Furthermore, the IRX4 gene may modulate cardiac development and function. Although the heart of Irx4- mice appears to develop normally, adult Irx4- mice exhibit cardiomyopathy, including cardiac hypertrophy and decreased contractility.

General readings

Ogura,K., et al., (2001) Cytogenet. Cell Genet. 92 (3-4), 320-325

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IRX1 / IRXA1 antibody

  Rabbit polyclonal anti-IRX1 antibody  
Western blot analysis of extracts from LOVO cells, using IRX1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

IRX1 / IRXA1 antibody

  Rabbit Polyclonal Anti-IRX1 Antibody  
WB Suggested Anti-IRX1 Antibody Titration: 1.25 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRX1 / IRXA1 antibody

  Rabbit Polyclonal Anti-IRX1 Antibody  
WB Suggested Anti-IRX1 Antibody Titration: 5.0 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IRX1 / IRXA1 antibody

  Rabbit Polyclonal Anti-IRX1 Antibody  
WB Suggested Anti-IRX1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Stomach Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

IRX1 / IRXA1 antibody

  Rabbit Polyclonal Anti-IRX1 Antibody  
WB Suggested Anti-IRX1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: Human Small Intestine Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

IRX1 / IRXA1 antibody

Immunohistochemistry analyzes of IRX1 antibody (Cat.-No.: AP20429PU-N) in paraffin-embedded human heart tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

IRX1 / IRXA1 antibody

Western blot analysis of extracts from LOVO cells, using IRX1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

IRX1 / IRXA1 antibody

Western blot analysis of extracts from LOVO cells, using IRX1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Irx1 - mouse gene knockout kit via CRISPR

Irx1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Irx1 - mouse gene knockout kit via CRISPR

Irx1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Irx1 - mouse gene knockout kit via CRISPR

Irx1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Irx1 - mouse gene knockout kit via CRISPR

Irx1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

IRX1 overexpression lysate

IRX1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, IRX1 (mGFP-tagged) - Human iroquois homeobox 1 (IRX1), 200 uL, >10^7 TU/mL

Lenti ORF particles, IRX1 (mGFP-tagged) - Human iroquois homeobox 1 (IRX1), 200 uL, >10^7 TU/mL  
200 µl / €1,100.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Irx1 (GFP-tagged) - Mouse Iroquois related homeobox 1 (Drosophila) (Irx1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Irx1 (GFP-tagged) - Mouse Iroquois related homeobox 1 (Drosophila) (Irx1), 200 uL, >10^7 TU/mL  
200 µl / €1,100.00
  OriGene Technologies, Inc.

Lenti ORF particles, Irx1 (Myc-DDK-tagged) - Mouse Iroquois related homeobox 1 (Drosophila) (Irx1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Irx1 (Myc-DDK-tagged) - Mouse Iroquois related homeobox 1 (Drosophila) (Irx1), 200 uL, >10^7 TU/mL  
200 µl / €980.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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