Islet-1 / ISL1 antibody

Principal name

Islet-1 / ISL1 antibody

Alternative names for Islet-1 / ISL1 antibody

Insulin gene enhancer protein ISL-1

SwissProt ID

P50211 (Chick), P61371 (Human), P61372 (Mouse), P61373 (Mesau), P61374 (Rat)

Gene ID

3670 (ISL1), 16392 (Isl1), 64444

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Ze (Zebrafish), African clawed frog

Available hosts

Goat, Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Islet-1 / ISL1 antibody

ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

De Luca, A., et al. Clin. Genet. (2010) In press
Davis, O.S., et al. Behav. Genet. (2010) In press
Genead, R., et al. Stem Cell Res 4(1):69-76(2010)
Stevens, K.N., et al. PLoS ONE 5 (5), E10855 (2010)
Zhang, H., et al. J. Mol. Biol. 392(3):566-577(2009)

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Islet-1 / ISL1 antibody

  Rabbit Polyclonal anti-ISL1 Antibody  
Host: Rabbit; Target Name: ISL1; Sample Tissue: Breast Tumor lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Islet-1 / ISL1 antibody

  Rabbit Polyclonal Anti-ISL1 Antibody  
WB Suggested Anti-ISL1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Muscle Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Islet-1 / ISL1 antibody

  ISL1 mouse monoclonal antibody, clone OTI2D8 (formerly 2D8)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ISL1 (RC206893, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ISL1.(1:500) Mouse IgG1 OTI2D8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Islet-1 / ISL1 antibody

Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and cervical carcinoma (right), showing nuclear localization using ISL1 antibody Cat.-No AM06335SU-N with DAB staining. Mouse IgG1 1H9 Ascites Hu E, ICC/IF, P, WB
0.1 ml / €440.00
  Acris Antibodies GmbH

Islet-1 / ISL1 antibody

Confocal Immunofluorescence analysis of HEK293 cells trasfected with full-length ISL1-hIgGFc using ISL1 antibody Cat.-No AM06336SU-N (green). Blue: DRAQ5 fluorescent DNA dye. Mouse IgG1 1B1 Ascites Hu E, ICC/IF, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

Islet-1 / ISL1 (Center) antibody

Western blot analysis of Islet-1 / ISL1 Antibody (Center) Cat.-No AP52244PU-N in mouse bladder tissue lysates (35ug/lane). This demonstrates the ISL1 antibody detected the ISL1 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Islet-1 / ISL1 antibody

Islet-1 ataining of mouse β-TC cells. Cells were stained using Rhodamine Red-conjugated donkey anti-goat secondary antibody. Goat Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €450.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

ISL1 - human gene knockout kit via CRISPR

ISL1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Isl1 - mouse gene knockout kit via CRISPR

Isl1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Isl1 - mouse gene knockout kit via CRISPR

Isl1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Isl1 - mouse gene knockout kit via CRISPR

Isl1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Isl1 - mouse gene knockout kit via CRISPR

Isl1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ISL1 overexpression lysate

ISL1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ISL1 (mGFP-tagged) - Human ISL LIM homeobox 1 (ISL1), 200 uL, >10^7 TU/mL

Lenti ORF particles, ISL1 (mGFP-tagged) - Human ISL LIM homeobox 1 (ISL1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ISL1 (Myc-DDK tagged) - Human ISL LIM homeobox 1 (ISL1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ISL1 (Myc-DDK tagged) - Human ISL LIM homeobox 1 (ISL1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Isl1 (Myc-DDK-tagged ORF) - Rat ISL LIM homeobox 1 (Isl1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Isl1 (Myc-DDK-tagged ORF) - Rat ISL LIM homeobox 1 (Isl1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

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