ITM2B antibody

Principal name

ITM2B antibody

Alternative names for ITM2B antibody

ITM2B, BRI, BRI2, Integral membrane protein 2B, Transmembrane protein BRI

SwissProt ID

O42204 (Chick), O89051 (Mouse), Q3T0P7 (Bovin), Q52N47 (Pig), Q5XIE8 (Rat), Q9Y287 (Human)

Gene ID

9445 (ITM2B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine)

Available hosts

Chicken, Mouse, Goat, Rabbit

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F)

Background of ITM2B antibody

Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-termil end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq].

General readings

Majewski T, Lee S, Jeong J, Yoon DS, Kram A, Kim MS, Tuziak T, Bondaruk J, Lee S, Park WS, Tang KS, Chung W, Shen L, Ahmed SS, Johnston DA, Grossman HB, Dinney CP, Zhou JH, Harris RA, Snyder C, Filipek S, Narod SA, Watson P, Lynch
HT, Gazdar A, Bar-Eli M, Wu XF, McConkey DJ, Baggerly K, Issa JP, Benedict WF, Scherer SE, Czerniak B.
Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.
Lab. Invest. 2008 Jul 88 (7): 694-721.
PMID: 18458673

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ITM2B antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ITM2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502734) Mouse IgG2a OTI1C11 Purified Hu F, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

ITM2B antibody

TA305731 (1ug/ml) staining of Human Hippocampus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ITM2B antibody

Figure 1. Western Blot of various organs stained with anti BRI (ITM2B), N-terminal B6 mouse strain.
a: cortex, b: cerebellum, c: heart, d: lung, e: liver, f: kidney, g: pancreas. Chicken Aff - Purified Hu C, WB
0.2 mg / €530.00
  Acris Antibodies GmbH

ITM2B antibody

ITM2B Chicken Aff - Purified Hu C
0.2 mg / €500.00
  Acris Antibodies GmbH

ITM2B antibody

Western Blot analysis of ITM2B expression in transfected 293T cell line (H00009445-T01) by ITM2B MaxPab polyclonal antibody.

Lane 1: ITM2B transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

ITM2B antibody

ITM2B Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

ITM2B antibody

Western Blot analysis of ITM2B expression in transfected 293T cell line (H00009445-T04) by ITM2B MaxPab polyclonal antibody.

Lane 1: ITM2B transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

ITM2B antibody

ITM2B MaxPab rabbit polyclonal antibody. Western Blot analysis of ITM2B expression in mouse liver. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

ITM2B antibody

Detection limit for recombinant GST tagged ITM2B is approximately 1ng/ml as a capture antibody. Mouse IgG2a 1A10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ITM2B antibody

ITM2B Goat IgG Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

ITM2B antibody

Immunohistochemistry-Paraffin: ITM2B Antibody [NBP1-88354] - Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity with a granular pattern in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ITM2B

ITM2B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

ITM2B

ITM2B Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

ITM2B

ITM2B Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

ITM2B

ITM2B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ITM2B

ITM2B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

ITM2B

ITM2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ITM2B

ITM2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ITM2B Lysate(Denatured)

ITM2B Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

ITM2B Lysate(Denatured)

ITM2B Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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