ITM2C / BRI3 antibody

Principal name

ITM2C / BRI3 antibody

Alternative names for ITM2C / BRI3 antibody

Cerebral protein 14, hucep-14, NPD018, PSEC0047, Integral membrane protein 2C, Transmembrane protein BRI3

SwissProt ID

A2VDN0 (Bovin), Q06AV4 (Pig), Q5PQL7 (Rat), Q91VK4 (Mouse), Q9BUP8 (Human), Q9NQX7 (Human)

Gene ID

81618 (ITM2C)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of ITM2C / BRI3 antibody

ITM2C is a negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-termil fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. ITM2C may also play a role in TNF-induced cell death and neurol differentiation By similarity.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ITM2C / BRI3 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ITM2C (RC200947, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ITM2C. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ITM2C / BRI3 antibody

Western Blot analysis of ITM2C expression in transfected 293T cell line (H00081618-T01) by ITM2C MaxPab polyclonal antibody.

Lane 1: ITM2C transfected lysate(25.41 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

ITM2C / BRI3 antibody

ELISA: ITM2C Antibody [31530002] - Affinity Purified Rabbit Hu E
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ITM2C / BRI3 (transcript variant 3)

ITM2C / BRI3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ITM2C 293T Cell Transient Overexpression Lysate(Denatured)

ITM2C 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

ITM2C overexpression lysate

ITM2C overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

ITM2C overexpression lysate

ITM2C overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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