IZUMO1 antibody

Principal name

IZUMO1 antibody

Alternative names for IZUMO1 antibody

Izumo sperm-egg fusion protein 1

SwissProt ID

Q6AY06 (Rat), Q8IYV9 (Human), Q9D9J7 (Mouse)

Gene ID

284359 (IZUMO1)

Available reactivities

Hu (Human)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of IZUMO1 antibody

IZUMO1, a sperm-specific protein, is essential for sperm-egg plasma membrane binding and fusion. It is involved in the fertilization process and in the fusion of the sperm with the egg (1,2). IZUMO1 is expressed as at least four isoforms produced by altertive splicing and contains one Ig-like (immunoglobulin-like) C2-type domain (3). Lack of IZUMO1 in males, due to homozygous mutation in the gene that encodes IZUMO1, results in sterility due to an ibility to penetrate the plasma membrane of the egg (4).

General readings

Saha,P., (er) Fertil. Steril. (2007) In press

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IZUMO1 antibody

WB Suggested Anti-IZUMO1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human heart Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

IZUMO1 antibody

Western blot analysis of IZUMO1 in human testis tissue lysate with IZUMO1 antibody at 1 ug/mL. Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IZUMO1 antibody

IZUMO1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

IZUMO1 antibody

Human Heart; WB Suggested Anti-IZUMO1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human heart; IZUMO1 antibody - C-terminal region (ARP51341_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

IZUMO1 antibody

Western Blot: IZUMO1 Antibody [NBP1-69692] - This Anti-IZUMO1 antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

IZUMO1 antibody

Immunohistochemistry-Paraffin: IZUMO1 Antibody [NBP1-83086] - Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IZUMO1

IZUMO1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates (Overexpressed)

Catalog No.    

IZUMO1 overexpression lysate

IZUMO1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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