JARID1C antibody

Principal name

JARID1C antibody

Alternative names for JARID1C antibody

Lysine-specific demethylase 5C, KDM5C, SMCX, XE169, DXS1272E, Histone demethylase JARID1C, Jumonji/ARID domain-containing protein 1C, Protein SmcX, Protein Xe169

SwissProt ID

A1YVX4 (Pig), P41229 (Human), P41230 (Mouse), Q38JA7 (Canfa)

Gene ID

8242 (KDM5C)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of JARID1C antibody

Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements.Tissue specificity:br>Involvement in disease:Defects in KDM5C are the cause of mental retardation syndromic X-linked JARID1C-related (MRXSJ) . MRXSJ is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRXSJ patients manifest mental retardation associated with variable features such as slowly progressive spastic paraplegia, seizures, facial dysmorphism.

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JARID1C antibody

Western blot detection of KDM5C / Jarid1C / SMCX in Hela and 293 cell lysates using KDM5C / Jarid1C / SMCX mouse mAb (1:1000 diluted).Predicted band size: 176KDa.Observed band size: 220KDa. Mouse IgG2a 2E4-E1-G8 Purified ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

JARID1C antibody

WB using the antibody against Jarid1c (lane 2) and with the preimmune serum (lane 1) diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. The position of the protein of interest is indicated on the right (expected size: 175 kDa); the marker (in kDa) is shown on the left. Image shows that the additional bands at approximately 55 and 80 kDa are also present in the preimmune serum. Rabbit IgG Purified Hu, Ms E
0.1 ml / €325.00
  OriGene Technologies, Inc.

JARID1C (C-term) antibody

Formalin-Fixed, Paraffin-Embedded Human Liver stained with JARID1C Antibody Cat.-No AM50089PU-N Mouse Purified Bov, Can, Hu, Ms, Rt ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

JARID1C antibody

JARID1C Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

JARID1C antibody

ELISA: SMCX Antibody [22270002] - Affinity Purified Rabbit Hu E, WB
50 µg / €520.00
  Novus Biologicals Inc.

JARID1C antibody

Western Blot and Immunoprecipitation: JARID1C Antibody [NB100-55327] - Detection of Human JARID1C on HeLa whole cell lysate using NB100-55327. JARID1C was also immunoprecipitated by rabbit anti-JARID1C antibody NB100-55328. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

JARID1C antibody

Western Blot and Immunoprecipitation: JARID1C Antibody [NB100-55328] - Detection of Human JARID1C on HeLa whole cell lysate using NB100-55328. JARID1C was also immunoprecipitated by rabbit anti-JARID1C antibody NB100-55327. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

7 Item(s)

per page
  • LinkedIn