JARID1D antibody

Principal name

JARID1D antibody

Alternative names for JARID1D antibody

Lysine-specific demethylase 5D, KDM5D, SMCY, HYA, HY, H-Y, Histone demethylase JARID1D, Jumonji/ARID domain-containing protein 1D, Protein SmcY, Histocompatibility Y antigen

SwissProt ID

Q30DN6 (Canfa), Q62240 (Mouse), Q9BY66 (Human)

Gene ID

8284 (KDM5D)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of JARID1D antibody

H-Y antigen is defined as a male histocompatibility antigen that causes rejection of male skin grafts by female recipients of the same inbred strain of rodents. Male-specific, or H-Y antigen(s), are also detected by cytotoxic T cells and antibodies. H-Y antigen appears to be an integral part of the membrane of most male cells. In addition, H-Y antibodies detect a soluble form of H-Y that is secreted by the testis. The gene (Smcy/SMCY) coding for H-Y antigen detected by T cells has been cloned. It is expressed ubiquitously in male mice and humans, and encodes an epitope that triggers a specific T-cell response in vitro. Additional epitopes coded for by different Y-chromosomal genes are probably required in vivo for the rejection of male grafts by female hosts. The molecular nature of H-Y antigen detected by antibodies on most male cells is not yet known. Testis-secreted, soluble H-Y antigen, however, was found to be identical to Müllerian-inhibiting substance (MIS). MIS cross-reacts with H-Y antibodies and identical findings were obtained for soluble H-Y antigen and MIS, i.e., secretion by testicular Sertoli and, to a lesser degree, ovarian cells, binding to a gonad-specific receptor, induction of gonadal sex reversal in vitro and, in cattle, in vivo. H-Y antisera also detect a molecule or molecules associated with the heterogametic sex in non-mammalian vertebrates. Molecular data on this antigen or antigens are not yet available.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JARID1D antibody

ELISA: JARID1D Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

JARID1D (C-term) antibody

Western analysis of recombinant human SMCY (Cat.-No AR60001PU-N) using anti-human SMCY / JARID1D polyclonal antibody Cat.-No. AP60001PU-N directed against the C-terminal part of human SMCY (Leu1248-Leu1539). Rabbit IgG Purified Hu WB
0.2 mg / €370.00
  Acris Antibodies GmbH

JARID1D (C-term) antibody

Western analysis of recombinant human SMCY (Cat.-No AR60001PU-N) using anti-human SMCY / JARID1D polyclonal antibody Cat.-No. AP60001PU-N directed against the C-terminal part of human SMCY (Leu1248-Leu1539). Rabbit IgG Purified Hu WB
0.1 mg / €270.00
  Acris Antibodies GmbH

JARID1D antibody

JARID1D Mouse IgG1 4C6 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

JARID1D antibody

ELISA: JARID1D Antibody [22240002] Rabbit Hu E, WB
50 µg / €580.00
  Novus Biologicals Inc.

JARID1D antibody

Western Blot: Jarid1D Antibody [NB100-93291] - Detection of Human SMCY/Jarid1D by Western Blot of  Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP,  20% of IP loaded) from Jurkat cells. Antibodies: Affinity  purified rabbit anti-SMCY/Jarid1D antibody NB100-93291 used  for IP at 3 mcg/mg lysate. SMCY/Jarid1D was also  immunoprecipitated by rabbit anti-SMCY/Jarid1D antibody  NB100-93292 which recognizes a downstream epitope Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

JARID1D antibody

Western Blot and Immunoprecipitation: Jarid1D Antibody [NB100-93292] - Detection of Human SMCY/Jarid1D on HeLa whole cell lysate using NB100-93292. SMCY/Jarid1D was also immunoprecipitated by rabbit anti-SMCY/Jarid1D antibody NB100-93291. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

JARID1D (His-tag)

SDS-PAGE analysis of recombinant human SMCY / JARID1D Cat.-No. AR60001PU-N. Sample was loaded in 15% SDS-polyacrylamide gel under reducing conditions and stained with Coomassie blue. Human Purified > 95 % by SDS-PAGE and Silver staining E. coli
25 µg / €350.00
  Acris Antibodies GmbH

JARID1D

JARID1D Human
10 µg / €380.00
  Abnova Taiwan Corp.

JARID1D

JARID1D Human
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

KDM5D overexpression lysate

KDM5D overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

11 Item(s)

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