JARID2 / Jumonji antibody

Principal name

JARID2 / Jumonji antibody

Alternative names for JARID2 / Jumonji antibody

JMJ, Jumonji/ARID domain-containing protein 2

SwissProt ID

Q62315 (Mouse), Q92833 (Human)

Gene ID

3720 (JARID2), 16468 (Jarid2)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat), Bov (Bovine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ChIP assay (ChIP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of JARID2 / Jumonji antibody

Jarid2 is a regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis.Jarid2 acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes.Jarid2 binds D and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells.Jarid2 does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases.Jarid2 also acts as a transcriptiol repressor of ANF via its interaction with GATA4 and NKX2-5.Jarid2 participates in the negative regulation of cell proliferation sigling.

17 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JARID2 / Jumonji antibody

  Rabbit Polyclonal JARID2 Antibody  
Western Blot: Jumonji/JARID2 Antibody - Detection of jumonji protein in E16 mouse brain lysate using 2ug/ml of anti-JARID2. Rabbit Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

JARID2 / Jumonji antibody

  Rabbit Polyclonal Anti-Jarid2 Antibody  
WB Suggested Anti-Jarid2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Mouse Liver Rabbit IgG Purified Can, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

JARID2 / Jumonji antibody

  Rabbit Polyclonal Anti-JARID2 Antibody - N-terminal region  
Host:Rabbit; Target Name:JARID2; Sample Tissue:721_B; Antibody Dilution: 1.0 ug/ml. JARID2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit IgG Purified Bov, GP, Hu, Ms, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

JARID2 / Jumonji antibody

  Rabbit Polyclonal JARID2 Antibody  
Determination of the antibody titer To determine the titer of the antibody, an ELISA was performed using a serial dilution of the antibody against human JARID2. The plates were coated with the peptides used for immunization of the rabbit. By plotting the absorbance against the antibody dilution (Figure 1), the titer of the antibody was estimated to be 1:9,300. Rabbit IgG Purified Hu E
0.1 ml / €325.00
  OriGene Technologies, Inc.

JARID2 / Jumonji (1-100) antibody

JARID2 staining of HeLa cells using a DyLight 488 conjugated secondary antibody. Rabbit IgG Aff - Purified Hu, Ms ChIP, ICC/IF, WB
0.1 ml / €380.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

JARID2 - human gene knockout kit via CRISPR

JARID2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

JARID2 - human gene knockout kit via CRISPR

JARID2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

JARID2 - human gene knockout kit via CRISPR

JARID2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

JARID2 - human gene knockout kit via CRISPR

JARID2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jarid2 - mouse gene knockout kit via CRISPR

Jarid2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Jarid2 - mouse gene knockout kit via CRISPR

Jarid2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jarid2 - mouse gene knockout kit via CRISPR

Jarid2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jarid2 - mouse gene knockout kit via CRISPR

Jarid2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

JARID2 overexpression lysate

JARID2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Lysates (Knockout)

Catalog No.    

JARID2-knockout Cell lysate

JARID2-knockout Cell lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, JARID2 (mGFP-tagged)-Human jumonji, AT rich interactive domain 2 (JARID2), 200 uL, >10^7 TU/mL

Lenti ORF particles, JARID2 (mGFP-tagged)-Human jumonji, AT rich interactive domain 2 (JARID2), 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, JARID2 (Myc-DDK-tagged)-Human jumonji, AT rich interactive domain 2 (JARID2), 200 uL, >10^7 TU/mL

Lenti ORF particles, JARID2 (Myc-DDK-tagged)-Human jumonji, AT rich interactive domain 2 (JARID2), 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

17 Item(s)

per page
  • LinkedIn