JIP-2 antibody

Principal name

JIP-2 antibody

Alternative names for JIP-2 antibody

JNK-interacting protein 2, MAPK8IP2, IB2, JIP2, PRKM8IPL, JIP2, Islet-brain-2, C-jun-amino-terminal kinase-interacting protein 2, JNK MAP kinase scaffold protein 2, Mitogen-activated protein kinase 8-interacting protein 2

SwissProt ID

Q13387 (Human), Q9ERE9 (Mouse)

Gene ID

23542 (MAPK8IP2), 60597 (Mapk8ip2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Prim (Primate), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of JIP-2 antibody

c-Jun amino-terminal kinase (JNK) is a member of the stress-activated group of mitogen-activated protein (MAP) kinases that are implicated in the control of cell growth. The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 plays a number of roles including IL1 beta-induced apoptosis inhibition in insulin-secreting cells; may function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins; interacts with components of the JNK signaling pathway namely JNK, MAPKK7 and MLK2, MLK3 and DLK; binds the proline-rich domain-containing splice variant of apolipoprotein E receptor 2 (ApoER2), the cytoplasmic tails of LRP1 and LRP2 (Megalin), the TPR motif-containing C-terminal of kinesin light chain and interacts with the cytoplasmic domain of APP. This protein has been classified as a housekeeping protein based on its essential role in cell physiology. Several splice variants are known with molecular weights (kDa)/pIs of 88.0/4.36 (isoform 1), 84.7/4.40 (isoform 2), 64.9/4.48 (isoform 3), 49.1/4.49 (isoform 4).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JIP-2 antibody

Adult rat brain membrane immunoblot Mouse IgG1 N135/37 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

JIP-2 antibody

Adult rat brain membrane immunoblot Mouse IgG1 N135/37 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

JIP-2 (226-421) antibody

JIP-2 Mouse IgG1 S135-37 Purified Ms, Rt ICC/IF, P, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

JIP-2 antibody

Immunohistochemistry (IHC) analyzes of JIP-2 antibody (Cat.-No.: AP06724PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

JIP-2 (C-term) antibody

JIP-2 Rabbit IgG Aff - Purified Hu, Prim WB
0.1 mg / €340.00
  Acris Antibodies GmbH

JIP-2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JIP2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

JIP-2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JIP2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

JIP-2 antibody

Immunohistochemical analysis of JIP2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt, Ze ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

JIP-2 antibody

Immunohistochemical analysis of JIP2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt, Ze ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

JIP-2 antibody

Immunohistochemical analysis of JIP2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt, Ze ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

JIP-2 antibody

Immunohistochemistry: JIP2 Antibody [NBP1-31411] - Immunohistochemical analysis of paraffin-embedded lung SCC , using NBP1-31411 at 1:100 dilution. Rabbit IgG Hu ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

JIP-2 antibody

Western Blot: JIP2 Antibody [NBP1-33035] - Western blot analysis of JIP2 on Molt-4 lysates using NBP1-33035. Rabbit IgG Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

JIP-2 antibody

JIP-2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

JIP-2 antibody

JIP-2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

JIP-2

JIP-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

JIP-2

JIP-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

JIP-2

JIP-2 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

JIP-2

JIP-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

JIP-2

JIP-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

JIP-2

JIP-2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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