JIP-2 antibody

Principal name

JIP-2 antibody

Alternative names for JIP-2 antibody

JNK-interacting protein 2, MAPK8IP2, IB2, JIP2, PRKM8IPL, JIP2, Islet-brain-2, C-jun-amino-terminal kinase-interacting protein 2, JNK MAP kinase scaffold protein 2, Mitogen-activated protein kinase 8-interacting protein 2

SwissProt ID

Q13387 (Human), Q9ERE9 (Mouse)

Gene ID

23542 (MAPK8IP2), 60597 (Mapk8ip2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of JIP-2 antibody

c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family. JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites, Ser 63 and Ser 73, resulting in transcriptional activation. Two additional JNK family members have been identified as JNK2 and JNK3. JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, thereby inhibiting JNK-regulated gene expression. Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, which are targets of the JNK signaling pathway. JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain. ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding. Multiple splice variants of JIP-1, including JIP-1b, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, have been identified in brain.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JIP-2 antibody

Adult rat brain membrane immunoblot Mouse IgG1 N135/37 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €460.00
  Antibodies Incorporated

NeuroMab

JIP-2 antibody

Adult rat brain membrane immunoblot Mouse IgG1 N135/37 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €540.00
  Antibodies Incorporated

NeuroMab

JIP-2 (226-421) antibody

JIP-2 Mouse IgG1 S135-37 Purified Ms, Rt ICC/IF, P, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

JIP-2 antibody

Immunohistochemistry (IHC) analyzes of JIP-2 antibody (Cat.-No.: AP06724PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

JIP-2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JIP2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

JIP-2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JIP2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

MAPK8IP2 - human gene knockout kit via CRISPR

MAPK8IP2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MAPK8IP2 - human gene knockout kit via CRISPR

MAPK8IP2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAPK8IP2 - human gene knockout kit via CRISPR

MAPK8IP2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAPK8IP2 - human gene knockout kit via CRISPR

MAPK8IP2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mapk8ip2 - mouse gene knockout kit via CRISPR

Mapk8ip2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Mapk8ip2 - mouse gene knockout kit via CRISPR

Mapk8ip2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mapk8ip2 - mouse gene knockout kit via CRISPR

Mapk8ip2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mapk8ip2 - mouse gene knockout kit via CRISPR

Mapk8ip2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MAPK8IP2 (mGFP-tagged) - Human mitogen-activated protein kinase 8 interacting protein 2 (MAPK8IP2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAPK8IP2 (mGFP-tagged) - Human mitogen-activated protein kinase 8 interacting protein 2 (MAPK8IP2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,720.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAPK8IP2 (Myc-DDK tagged) - Human mitogen-activated protein kinase 8 interacting protein 2 (MAPK8IP2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, MAPK8IP2 (Myc-DDK tagged) - Human mitogen-activated protein kinase 8 interacting protein 2 (MAPK8IP2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,550.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Mapk8ip2 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 2 (Mapk8ip2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip2 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 2 (Mapk8ip2), 200 uL, >10^7 TU/mL  
200 µl / €1,560.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mapk8ip2 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 2 (Mapk8ip2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip2 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 2 (Mapk8ip2), 200 uL, >10^7 TU/mL  
200 µl / €1,400.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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