JIP-3 antibody

Principal name

JIP-3 antibody

Alternative names for JIP-3 antibody

JNK-interacting protein 3, MAPK8IP3, JIP3, C-jun-amino-terminal kinase-interacting protein 3, JNK MAP kinase scaffold protein 3, Mitogen-activated protein kinase 8-interacting protein 3

SwissProt ID

O13555 (Yeast), Q9ESN9 (Mouse), Q9UPT6 (Human)

Gene ID

23162 (MAPK8IP3), 30957 (Mapk8ip3)

Available reactivities

Ms (Mouse), Hu (Human), Bov (Bovine), Rt (Rat)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of JIP-3 antibody

c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family. JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites Ser 63 and Ser 73, resulting in transcriptional activation. Two additional JNK family members, JNK2 and JNK3, have been identified. JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, thereby inhibiting JNK-regulated gene expression. Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, which are targets of the JNK signaling pathway. JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain. ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding. Multiple splice variants of JIP-1, including JIP-1b, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, have been identified in brain.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JIP-3 antibody

  Goat Anti-MAPK8IP3 / JIP3 Antibody  
(4ug/ml) staining of paraffin embedded Mouse Brain. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Bov, Hu, Ms, Rt E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

JIP-3 antibody

  Rabbit polyclonal anti-MAPK8IP3 / JIP3 antibody  
Western blot analysis of extracts from HeLa cells, using JIP3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

JIP-3 antibody

Immunohistochemistry (IHC) analyzes of JIP-3 antibody (Cat.-No.: AP01286PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

JIP-3 antibody

Immunofluorescence analysis of HeLa cells, using JIP3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

JIP-3 antibody

Immunofluorescence analysis of HeLa cells, using JIP3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

MAPK8IP3 - human gene knockout kit via CRISPR

MAPK8IP3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MAPK8IP3 - human gene knockout kit via CRISPR

MAPK8IP3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAPK8IP3 - human gene knockout kit via CRISPR

MAPK8IP3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAPK8IP3 - human gene knockout kit via CRISPR

MAPK8IP3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mapk8ip3 - mouse gene knockout kit via CRISPR

Mapk8ip3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Mapk8ip3 - mouse gene knockout kit via CRISPR

Mapk8ip3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mapk8ip3 - mouse gene knockout kit via CRISPR

Mapk8ip3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mapk8ip3 - mouse gene knockout kit via CRISPR

Mapk8ip3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MAPK8IP3 (mGFP-tagged)-Human mitogen-activated protein kinase 8 interacting protein 3 (MAPK8IP3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAPK8IP3 (mGFP-tagged)-Human mitogen-activated protein kinase 8 interacting protein 3 (MAPK8IP3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAPK8IP3 (Myc-DDK-tagged)-Human mitogen-activated protein kinase 8 interacting protein 3 (MAPK8IP3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAPK8IP3 (Myc-DDK-tagged)-Human mitogen-activated protein kinase 8 interacting protein 3 (MAPK8IP3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,440.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €2,210.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 6, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €2,180.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 7, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 7, 200 uL, >10^7 TU/mL  
200 µl / €2,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mapk8ip3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,200.00
  OriGene Technologies, Inc.

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