JIP-3 antibody

Principal name

JIP-3 antibody

Alternative names for JIP-3 antibody

JNK-interacting protein 3, MAPK8IP3, JIP3, C-jun-amino-terminal kinase-interacting protein 3, JNK MAP kinase scaffold protein 3, Mitogen-activated protein kinase 8-interacting protein 3

SwissProt ID

O13555 (Yeast), Q9ESN9 (Mouse), Q9UPT6 (Human)

Gene ID

23162 (MAPK8IP3), 30957 (Mapk8ip3)

Available reactivities

Ms (Mouse), Hu (Human), Bov (Bovine), Rt (Rat)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of JIP-3 antibody

c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family. JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites Ser 63 and Ser 73, resulting in transcriptional activation. Two additional JNK family members, JNK2 and JNK3, have been identified. JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, thereby inhibiting JNK-regulated gene expression. Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, which are targets of the JNK signaling pathway. JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain. ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding. Multiple splice variants of JIP-1, including JIP-1b, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, have been identified in brain.

12 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JIP-3 antibody

(4ug/ml) staining of paraffin embedded Mouse Brain. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Bov, Hu, Ms, Rt E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

JIP-3 antibody

Western blot analysis of extracts from HeLa cells, using JIP3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

JIP-3 antibody

Immunohistochemistry (IHC) analyzes of JIP-3 antibody (Cat.-No.: AP01286PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

JIP-3 antibody

JIP-3 Goat Ms E
0.1 mg / €400.00
  Abnova Taiwan Corp.

JIP-3 antibody

Immunofluorescence analysis of HeLa cells, using JIP3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

JIP-3 antibody

Immunofluorescence analysis of HeLa cells, using JIP3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

JIP-3 antibody

Immunohistochemical analysis of JIP3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

JIP-3 antibody

Immunohistochemical analysis of JIP3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

JIP-3 antibody

Immunohistochemical analysis of JIP3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €2,210.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 7, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip3 (GFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 7, 200 uL, >10^7 TU/mL  
200 µl / €2,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mapk8ip3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 7, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mapk8ip3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 7, 200 uL, >10^7 TU/mL  
200 µl / €1,960.00
  OriGene Technologies, Inc.

12 Item(s)

per page
  • LinkedIn