JMJD1B / KDM3B antibody

Principal name

JMJD1B / KDM3B antibody

Alternative names for JMJD1B / KDM3B antibody

5qNCA, C5orf7, JHDM2B, KIAA1082, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA, Lysine-specific demethylase 3B

SwissProt ID

Q6ZPY7 (Mouse), Q7LBC6 (Human)

Gene ID

51780 (KDM3B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Flow Cytometry (F)

Background of JMJD1B / KDM3B antibody

The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene. Besides CD34+ cells and acute myeloid leukemia (AML) cell lines, JMJD1B mRNA is highly expressed in liver, heart, kidney, skeletal muscle, and placenta tissues. The JMJD1B gene is localized to a region of chromosome 5q31, which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor. In contrast, JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung cancers indicating that the role of JMJD1B in cancer formation and progression is more complex than originally postulated. At least three isoforms of JMJD1B are known to exist.

General readings

Guo, G., et al. Dev. Cell 18(4):675-685(2010)
Allis, C.D., et al. Cell 131(4):633-636(2007)
Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004)
Okazaki, N., et al. DNA Res. 10(4):167-180(2003)
Stryke, D., et al. Nucleic Acids Res. 31(1):278-281(2003)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JMJD1B / KDM3B antibody

  Rabbit Polyclonal JMJD1B Antibody  
Western blot analysis of JMJD1B in rat liver tissue lysate with JMJD1B antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD1B / KDM3B antibody

  Rabbit Polyclonal Anti-JMJD1B Antibody  
WB Suggested Anti-JMJD1B Antibody Titration: 2.5 ug/ml; ELISA Titer: 1: 12500; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD1B / KDM3B antibody

  Rabbit Polyclonal Anti-KDM3B Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Hela cells, 293T cells, mouse skeletal muscle tissue, Primary antibody: (KDM3B Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

JMJD1B / KDM3B (N-term) antibody

Figure 1. Western blot analysis of anti-JMJD1B (N-term) Pab in Ramos cell line lysate. JMJD1B (N-term) (Cat. #AP11040PU-N) (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

JMJD1B / KDM3B antibody

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

JMJD1B / KDM3B (Center) antibody

Western blot analysis of JHDM2b Antibody (Center) Cat.-No AP52266PU-N in Ramos cell line lysates (35ug/lane). This demonstrates the JHDM2b antibody detected the JHDM2b protein (arrow). Rabbit Ig Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

JMJD1B / KDM3B (C-term) antibody

Western blot analysis of JHDM2b Antibody (C-term) Cat.-No AP52267PU-N in mouse heart tissue lysates (35ug/lane). This demonstrates the JHDM2b antibody detected the JHDM2b protein (arrow). Rabbit Ig Purified Hu, Ms F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

KDM3B - human gene knockout kit via CRISPR

KDM3B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KDM3B - human gene knockout kit via CRISPR

KDM3B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KDM3B - human gene knockout kit via CRISPR

KDM3B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KDM3B - human gene knockout kit via CRISPR

KDM3B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

11 Item(s)

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