JMJD1B / KDM3B antibody

Principal name

JMJD1B / KDM3B antibody

Alternative names for JMJD1B / KDM3B antibody

5qNCA, C5orf7, JHDM2B, KIAA1082, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA, Lysine-specific demethylase 3B

SwissProt ID

Q6ZPY7 (Mouse), Q7LBC6 (Human)

Gene ID

51780 (KDM3B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of JMJD1B / KDM3B antibody

The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene. Besides CD34+ cells and acute myeloid leukemia (AML) cell lines, JMJD1B mRNA is highly expressed in liver, heart, kidney, skeletal muscle, and placenta tissues. The JMJD1B gene is localized to a region of chromosome 5q31, which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor. In contrast, JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung cancers indicating that the role of JMJD1B in cancer formation and progression is more complex than originally postulated. At least three isoforms of JMJD1B are known to exist. This antibody will not cross-react with JMJD1A or JMJD1C.

General readings

Guo, G., et al. Dev. Cell 18(4):675-685(2010)
Allis, C.D., et al. Cell 131(4):633-636(2007)
Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004)
Okazaki, N., et al. DNA Res. 10(4):167-180(2003)
Stryke, D., et al. Nucleic Acids Res. 31(1):278-281(2003)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JMJD1B / KDM3B antibody

Western blot analysis of JMJD1B in rat liver tissue lysate with JMJD1B antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD1B / KDM3B antibody

WB Suggested Anti-JMJD1B Antibody Titration: 2.5 ug/ml; ELISA Titer: 1: 12500; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD1B / KDM3B (N-term) antibody

Figure 1. Western blot analysis of anti-JMJD1B (N-term) Pab in Ramos cell line lysate. JMJD1B (N-term) (Cat. #AP11040PU-N) (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

JMJD1B / KDM3B antibody

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

JMJD1B / KDM3B Control Peptide

JMJD1B / KDM3B
50 µg / €160.00
  Acris Antibodies GmbH

JMJD1B / KDM3B (Center) antibody

Western blot analysis of JHDM2b Antibody (Center) Cat.-No AP52266PU-N in Ramos cell line lysates (35ug/lane). This demonstrates the JHDM2b antibody detected the JHDM2b protein (arrow). Rabbit Ig Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

JMJD1B / KDM3B (C-term) antibody

Western blot analysis of JHDM2b Antibody (C-term) Cat.-No AP52267PU-N in mouse heart tissue lysates (35ug/lane). This demonstrates the JHDM2b antibody detected the JHDM2b protein (arrow). Rabbit Ig Purified Hu, Ms F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

JMJD1B / KDM3B antibody

Western Blot analysis of JMJD1B expression in transfected 293T cell line (H00051780-T01) by JMJD1B MaxPab polyclonal antibody.

Lane 1: JMJD1B transfected lysate(83.49 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

JMJD1B / KDM3B antibody

JMJD1B / KDM3B Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

JMJD1B / KDM3B antibody

Western blot analysis of JMJD1B polyclonal antibody ( Cat # PAB2196 ) in Ramos cell line lysate. JMJD1B ( N-term ) ( arrow ) was detected using the purified polyclonal antibody. Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

JMJD1B / KDM3B antibody

JMJD1B / KDM3B Rabbit IgG Aff - Purified Ms WB
50 µg / €680.00
  Funakoshi Co., Ltd.

JMJD1B / KDM3B antibody

Immunohistochemistry-Paraffin: JMJD1B Antibody [NB110-38879] - FFPE section of human prostate adenocarcinoma.   Affinity purified rabbit anti-JMJD1B used at a dilution of 1:250.  DAB staining using Immunohistochemistry Accessory Kit Rabbit Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

JMJD1B / KDM3B antibody

Immunohistochemistry-Paraffin: JMJD1B Antibody [NBP1-77071] - Rat liver tissue with JMJD1B antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

JMJD1B / KDM3B antibody

Immunohistochemistry-Paraffin: JMJD1B Antibody [NBP1-88256] - staining of human fallopian tube shows nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

JMJD1B / KDM3B

JMJD1B / KDM3B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

JMJD1B / KDM3B

JMJD1B / KDM3B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

JMJD1B 293T Cell Transient Overexpression Lysate(Denatured)

JMJD1B 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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