JMJD1C / TRIP8 antibody

Principal name

JMJD1C / TRIP8 antibody

Alternative names for JMJD1C / TRIP8 antibody

JHDM2C, KIAA1380, Probable JmjC domain-containing histone demethylation protein 2C, Jumonji domain-containing protein 1C, Thyroid receptor-interacting protein 8

SwissProt ID

Q15652 (Human), Q69ZK6 (Mouse)

Gene ID

221037 (JMJD1C)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of JMJD1C / TRIP8 antibody

The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JMJD1C / TRIP8 antibody

  Rabbit Polyclonal JMJD1C Antibody  
Western blot analysis of JMJD1C in human liver tissue lysate with JMJD1C antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD1C / TRIP8 antibody

  Rabbit Polyclonal JMJD1C Antibody  
ELISA: JMJD1C Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD1C / TRIP8 (N-term) antibody

Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

JMJD1C - human gene knockout kit via CRISPR

JMJD1C - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

JMJD1C - human gene knockout kit via CRISPR

JMJD1C - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

JMJD1C - human gene knockout kit via CRISPR

JMJD1C - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

JMJD1C - human gene knockout kit via CRISPR

JMJD1C - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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