JMJD2A / KDM4A antibody

Principal name

JMJD2A / KDM4A antibody

Alternative names for JMJD2A / KDM4A antibody

JHDM3A, JMJD2, KIAA0677, JmjC domain-containing histone demethylation protein 3A, Lysine-specific demethylase 4A, Jumonji domain-containing protein 2A

SwissProt ID

O75164 (Human), Q8BW72 (Mouse), Q9V333 (Drome)

Gene ID

9682 (KDM4A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of JMJD2A / KDM4A antibody

Jumonji lysine demethylases (JMJDs) are oxygeses catalyzing demethylation of mono-, di-, or trimethylated lysines, and its members (JMJD2A, JMJD2B, JMJD2C, and JMJD2D) are Fe(II)- and alpha-ketoglutarate-dependent enzymes harboring a JmjC catalytic domain. JMJD2A (JHDM3 or KDM4A) catalyzes the demethylation of di- and trimethylated H3K9 and H3K36 and participate in transcriptiol repression of ASCL2 and E2F-responsive promoters via the recruitment of HDACs and NCOR1, respectively. JMJD2A as well as JMJD2C have been suggested to act as co-activators of AR-dependent gene transcription. JMJD2A is widely expressed in human tissues and cell lines with high expression in human T-cell lymphotropic virus 1-infected cell lines, HT1376 bladder carcinoma cell line, U2OS osteosarcoma cell line and prostate cancer cell lines. JMJD2A is overexpressed in mouse and human lung cancers has been proposed as an oncogene that represents a target for Ras-expressing tumors. Silencing of JMJD2A gene has been shown to result in cell cycle change and proliferation inhibition, and suppression of tumor cell migration/ invasion.

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JMJD2A / KDM4A antibody

Western blot analysis of JMJD2A in rat liver tissue lysate with JMJD2A antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD2A / KDM4A antibody

Western Blot: JMJD2A Antibody [TA336795] - Analysis of JMJDA in HeLa nuclear extracts. Rabbit Purified Hu, Ms C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

JMJD2A / KDM4A antibody

WB using the antibody against JMJD2a diluted 1:500 in TBS-Tween containing 5% skimmed milk. The position of the protein of interest is indicated on the right (expected size 121 kDa); the marker (in kDa) is shown on the left. Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

JMJD2A / KDM4A antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with HA-tagged JMJD2A and untagged Kv2.1 plasmids and probed with N154/32 (left) and K89/41 (right). Mouse IgG1 N154/32 Supernatant Hu ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

JMJD2A / KDM4A antibody

Transfected cell immunoblot: extracts of COS cells transiently transfected with HA-tagged JMJD2A and untagged Kv2.1 plasmids and probed with N154/32 (left) and K89/41 (right). Mouse IgG1 N154/32 Purified Hu ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

JMJD2A / KDM4A antibody

Immunohistochemical analysis of paraffin-embedded colon cancer tissues (left) and human larynx cancer tissues (right) using KDM4A antibody Cat.-No AM06496SU-N with DAB staining. Mouse IgG1 5H1 Ascites Hu E, ICC/IF, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

JMJD2A / KDM4A (N-term) antibody

Western blot analysis of JMJD2A (arrow) using rabbit polyclonal JMJD2A Antibody (N-term) (Cat.#AP11068PU-N). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the JMJD2A gene (Lane 2) (Origene Technologies). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

JMJD2A / KDM4A antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

JMJD2A / KDM4A Control Peptide

JMJD2A / KDM4A
50 µg / €160.00
  Acris Antibodies GmbH

JMJD2A / KDM4A antibody

Nuclear extracts from HeLa cells ( 40 µg ) were analysed by Western blot using JMJD2A polyclonal antibody ( Cat # PAB14135 ) diluted 1 : 500 in TBS-Tween containing 5% skimmed milk. Rabbit Hu E, WB
50 µg / €390.00
  Abnova Taiwan Corp.

JMJD2A / KDM4A antibody

JMJD2A / KDM4A Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

JMJD2A / KDM4A antibody

JMJD2A / KDM4A Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

JMJD2A / KDM4A antibody

JMJD2A / KDM4A Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

JMJD2A / KDM4A antibody

JMJD2A / KDM4A Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

JMJD2A / KDM4A antibody

JMJD2A / KDM4A Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

JMJD2A / KDM4A antibody

JMJD2A / KDM4A Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
25 µl / €160.00
  Novus Biologicals Inc.

JMJD2A / KDM4A antibody

Immunohistochemistry-Paraffin: JMJD2A Antibody (5H1) [NBP1-51642] - Immunohistochemical analysis of paraffin-embedded colon cancer tissues (left) and human larynx cancer tissues (right) using KDM4A mouse mAb with DAB staining. Mouse IgG1 5H1 Purified Hu E, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

JMJD2A / KDM4A

JMJD2A / KDM4A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

18 Item(s)

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