JMJD3 / KDM6B antibody

Principal name

JMJD3 / KDM6B antibody

Alternative names for JMJD3 / KDM6B antibody

KIAA0346, Histone demethylase JMJD3,JmjC domain-containing protein 3, Jumonji domain-containing protein 3, Lysine demethylase 6B

SwissProt ID

O15054 (Human), Q5NCY0 (Mouse)

Gene ID

23135 (KDM6B), 216850 (Kdm6b)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat), African clawed frog, Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of JMJD3 / KDM6B antibody

Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.

General readings

Agger K, Cloos PA, Christensen J, et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 2007; 449:731-4.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JMJD3 / KDM6B antibody

Western Blot: JMJD3 Antibody - Western Blot on HepG2 cell lysates. Rabbit Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

JMJD3 / KDM6B (N-term) antibody

Western blot analysis of JMJD3 in K562 cell lysate with JMJD3 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD3 / KDM6B (N-term) antibody

Western blot analysis of anti-JMJD3 (N-term) Pab (TA324360) in Hela cell line lysates. JMJD3 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

JMJD3 / KDM6B antibody

WB Suggested Anti-JMJD3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Lung Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

JMJD3 / KDM6B antibody

WB Suggested Anti-JMJD3 Antibody Titration: 1.25 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD3 / KDM6B (C-term) antibody

Formalin-fixed and paraffin-embedded human Skeletal Muscle tissue reacted with JMJD3 Antibody (C-term) Cat.-No AP11033PU-N, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

JMJD3 / KDM6B (Center) antibody

Figure 1. Western blot analysis of anti-JMJD3 Center Pab (Cat.#AP11034PU-N) in 293 cell line lysates. JMJD3 Center(arrow) was detected using the purified Pab. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

JMJD3 / KDM6B (N-term) Control Peptide

Western blot analysis of JMJD3 in K562 cell lysate with JMJD3 antibody Cat.-No AP55610PU-N at 0.5 µg/ml in (A) the absence and (B) the presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

JMJD3 / KDM6B antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with JMJD3 polyclonal antibody ( Cat # PAB2188 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

JMJD3 / KDM6B antibody

Western blot analysis of Jmjd3 polyclonal antibody ( Cat # PAB2189 ) in untransfected 293 cells ( left ) and transfected 293 cells ( right ) . The detection of a prominent band at 180kDa is observed on transfected 293 cells but not on the untransfected 293 cells. Data kindly provided by Dr.Gioacchino Natoli of European Institute of Oncology. Rabbit Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

JMJD3 / KDM6B antibody

Western blot analysis of Jmjd3 polyclonal antibody ( Cat # PAB2190 ) in 293 cell line lysates. Jmjd3 Center ( arrow ) was detected using the purified polyclonal antibody. Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

JMJD3 / KDM6B antibody

Human Lung; WB Suggested Anti-JMJD3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Lung; JMJD3 antibody - N-terminal region (ARP40101_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

JMJD3 / KDM6B antibody

HepG2; Host: Rabbit. Target Name:JMJD3. Sample Tissue:HepG2. Lane A: Primary Antibody . Lane B: Primary Antibody + Blocking Peptide . Primary Antibody Concentration:2.5ug/mL. Peptide Concentration: 2.0ug/mL. Lysate Quantity: 25ug/lane. Gel Concentration: 6%-18%.; JMJD3 antibody - middle region (ARP40102_T100) in HepG2 cells using Western Blot Rabbit Purified African clawed frog, Can, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

JMJD3 / KDM6B antibody

JMJD3 / KDM6B Rabbit Biotin Hu, Ms WB
0.1 ml / €360.00
  Novus Biologicals Inc.

JMJD3 / KDM6B antibody

JMJD3 / KDM6B Rabbit DyLight488 Hu, Ms WB
0.1 ml / €390.00
  Novus Biologicals Inc.

JMJD3 / KDM6B antibody

JMJD3 / KDM6B Rabbit HRP Hu, Ms WB
0.1 ml / €390.00
  Novus Biologicals Inc.

JMJD3 / KDM6B

JMJD3 / KDM6B E, WB
50 µg / €140.00
  Novus Biologicals Inc.

JMJD3 / KDM6B antibody

JMJD3 / KDM6B Rabbit Aff - Purified Hu, Ms, Rt WB
25 µl / €200.00
  Novus Biologicals Inc.

Western Blot/IP/ChiP Kits

Catalog No. Host Iso. Clone Pres. React. Applications  

JMJD3 Western Blot Kit

JMJD3 Western Blot Kit Hu
25 Western Blots / kit / €640.00
  AVIVA Systems Biology

JMJD3 Western Blot kit

JMJD3 Western Blot kit
1 kit / €640.00
  AVIVA Systems Biology

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