JMJD6 / PTDSR antibody

Principal name

JMJD6 / PTDSR antibody

Alternative names for JMJD6 / PTDSR antibody

KIAA0585, Phosphatidylserine receptor, Histone arginine demethylase JMJD6, JmjC domain-containing protein 6, Jumonji domain-containing protein 6

SwissProt ID

Q58DS6 (Bovin), Q5ZMK5 (Chick), Q6AYK2 (Rat), Q6NYC1 (Human), Q9ERI5 (Mouse)

Gene ID

360665 (Jmjd6), 23210 (JMJD6)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of JMJD6 / PTDSR antibody

Most cells that undergo apoptosis are rapidly recognized, engulfed, and digested by professional phagocytes or by neighboring cells and eliminated from the organism. In this way, tissue exposure to potentially cytotoxic, immunogenic, or inflammatory cellular contents is prevented. As a result neither inflammation nor inappropriate immune responses are induced in this process. Removal of apoptotic cells comprise the following steps: surface alteration and ligand expression on the apoptotic cell, ligand recognition by tethering receptors on the phagocyte, initiation of appropriate signaling pathways in the phagocyte, engulfment and finally, digestion. Various molecules including proteins, carbohydrates, and phospholipids have been suggested to act as cell surface exposed markers for recognition by phagocytes. Virtually all apoptotic cells permanently express phosphatidylserine (PS) on the outer leaflet of their plasma membrane. Such loss of phospholipids asymmetry and exposure of PS does not occur in resting cells and appears only transiently following activation of certain cells. Phosphatidylserine Receptor (PSR) has been reported and shown to recognize phosphatidylserine in a stereospecific manner. PSR is an evolutionarily conserved glycoprotein that is widely expressed in cells and tissues. It is very susceptible to cleavage by protease or elastase. PSR engagement plays an important role in macropinocytosis and uptake of tethered apoptotic cells. Cooperation with other receptors and their ligands may also be needed for ingestion of apoptotic cells. PSR is also involved in suppression of inflammatory and immune responses.

General readings

Hong X. et al. (2010) Proc. Natl. Acad. Sci. u.S.A. 107:14568-14572.Webby C.J. et al. (2009) Science 325:90-93.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JMJD6 / PTDSR antibody

Western blot analysis of JMJD6 in human brain tissue lysate with JMJD6 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD6 / PTDSR antibody

Sample (30 ug of whole cell lysate). . A: A431 . . 10% SDS PAGE. . TA308580 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

JMJD6 / PTDSR antibody

Western blot analysis of extracts of various cell lines, using JMJD6 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD6 / PTDSR antibody

Western Blot: JMJD6 Antibody [TA336815] - Analysis of JMJD6 in A431 cell lysate. Rabbit Purified Hu ICC/IF, WB
50 µl / €325.00
  OriGene Technologies, Inc.

JMJD6 / PTDSR antibody

WB Suggested Anti-JMJD6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

JMJD6 / PTDSR antibody

WB Suggested Anti-PTDSR Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

JMJD6 / PTDSR antibody

Western blot detection of JMJD6(N-terminus) in Hela and HL-60 lysates using JMJD6(N-terminus) mouse mAb (1:1000 diluted).Predicted band size: 46KDa.Observed band size: 62KDa. Mouse IgG1 3G5-G5-H8 Purified ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

JMJD6 / PTDSR (N-term) antibody

Western blot analysis of anti-PTDSR (N-term) Pab (Cat.#AP11061PU-N) in mouse heart, Hela, and HL60 cell line lysates. PTDSR (N-term) (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu, Ms WB

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

JMJD6 / PTDSR Control Peptide

JMJD6 / PTDSR
50 µg / €160.00
  Acris Antibodies GmbH

JMJD6 / PTDSR antibody

JMJD6 / PTDSR Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

JMJD6 / PTDSR antibody

JMJD6 / PTDSR Mouse IgG 6G10 Purified Hu WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

JMJD6 / PTDSR antibody

Western blot analysis of JMJD6 polyclonal antibody ( Cat # PAB2219 ) in mouse heart, Hela, and HL-60 cell line lysates. PTDSR ( N-term ) ( arrow ) was detected using the purified polyclonal antibody. Rabbit Hu, Ms E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

JMJD6 / PTDSR antibody

Human Breast; IHC Suggested Anti-PTDSR antibody . Titration: 5ug/ ml. Positive Control: Breast; PTDSR antibody - middle region (ARP31807_P050) in Human Breast cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

JMJD6 / PTDSR antibody

Human HeLa; WB Suggested Anti-JMJD6 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Hela cell lysate; JMJD6 antibody - N-terminal region (ARP39180_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

JMJD6 / PTDSR antibody

Human Thymus; WB Suggested Anti-PTDSR Antibody Titration: 1.25ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Thymus; PTDSR antibody - C-terminal region (ARP39181_T100) in Human Thymus cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

JMJD6 / PTDSR antibody

Immunohistochemistry: JMJD6 Antibody [NBP1-32978] - Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using NBP1-32978. Rabbit IgG Hu P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

JMJD6 / PTDSR antibody

Immunohistochemistry-Paraffin: JMJD6 Antibody [NBP1-77075] - Rat brain tissue with JMJD6 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

JMJD6 / PTDSR (transcript variant 2)

JMJD6 / PTDSR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

JMJD6 / PTDSR (transcript variant 1)

JMJD6 / PTDSR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

JMJD6 / PTDSR (1-414, His-tag)

JMJD6 / PTDSR Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

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