JTB antibody

Principal name

JTB antibody

Alternative names for JTB antibody

PAR protein, Jumping translocation breakpoint protein, Prostate androgen-regulated protein

SwissProt ID

O76095 (Human), O88823 (Rat), O88824 (Mouse)

Gene ID

10899 (JTB)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of JTB antibody

Jumping translocation breakpoint, also known as JTB, is required for normal cytokinesis during mitosis. This protein plays a role in the regulation of cell proliferation. This protein may be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. It lnhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.

General readings

Platica M., et al. (2011) Int. J. Oncol. 38:777-785Kanome T., et al. (2007) Oncogene. 26:5991-6001

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

JTB antibody

JTB polyclonal antibody (A01), Lot # NBI0061124QCS1 Western Blot analysis of JTB expression in IMR-32 ( Cat # L008V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

JTB antibody

JTB Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

JTB antibody

Western Blot analysis of JTB expression in transfected 293T cell line (H00010899-T02) by JTB MaxPab polyclonal antibody.

Lane 1: JTB transfected lysate(16.06 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

JTB antibody

Detection limit for recombinant GST tagged JTB is approximately 1ng/ml as a capture antibody. Mouse IgG2a 4E7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

JTB (31-105, His-tag)

JTB Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

JTB (31-105, His-tag)

JTB Human Purified > 85 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

JTB

JTB Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

JTB

JTB Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

JTB 293T Cell Transient Overexpression Lysate(Denatured)

JTB 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

JTB 293T Cell Transient Overexpression Lysate(Denatured)

JTB 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

JTB overexpression lysate

JTB overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

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