Jun-D antibody

Principal name

Jun-D antibody

Alternative names for Jun-D antibody

JUND, Transcription factor jun-D

SwissProt ID

A7YY54 (Bovin), P15066 (Mouse), P17535 (Human), P27921 (Chick), P52909 (Rat)

Gene ID

3727 (JUND), 24518 (Jund), 16478

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Immunoprecipitation (IP), Frozen Sections (C), Electrophoretic Mobility Shift Assay (EMSA)

Background of Jun-D antibody

JunD is the most broadly expressed member of the Jun family and the AP1 transcription factor complex. It has been found that primary fibroblasts lacking murine JunD displayed p53-dependent growth arrest, upregulated p19(ARF) expression, and premature senescence. In contrast, immortalized cell lines lacking JunD showed increased proliferation and higher cyclin D1 levels. These properties were reminiscent of the effects of oncogenic RAS expression on primary and established cell cultures. Furthermore, JunD -/- fibroblasts exhibited increased p53-dependent apoptosis upon ultraviolet irradiation and were sensitive to the cytotoxic effects of tumor necrosis factor-alpha. The antiapoptotic role of JunD was confirmed using an in vivo model of TNF-mediated hepatitis. The authors proposed that JunD protects cells from senescence, or apoptotic responses to stress stimuli, by acting as a modulator of the signaling pathways that link RAS to p53.

General readings

Ota,T., et al., (2005) Oncogene 24 (51), 7567-7578

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Jun-D antibody

Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-JUND Rabbit Polyclonal antibody. (TA590607) Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Jun-D antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JunD antibody Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €270.00
  Acris Antibodies GmbH

Jun-D antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JunD antibody Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

Jun-D antibody

Western blot analysis of extracts from HeLa cells using JunD antibody. Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Jun-D antibody

Western blot analysis of extracts from Jurkat cells, using JunD (Ab-255) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Jun-D antibody

Predicted band size: 35 kDa . Positive control: Jurkat cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/800 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Jun-D antibody

Predicted cell location: Nucleus. Positive control: Human ovarian and breast cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using JUND antibody at dilution 1/60, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Jun-D antibody

Western blot analysis of JunD phosphorylation expression in 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Jun-D (C-term) antibody

TA326732 (1µg/ml) staining of NIH3T3 nuclear lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Jun-D antibody

Jun-D Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Jun-D antibody

Western blot analysis of extracts of various cell lines, using JUND antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Jun-D antibody

Western blot analysis of extracts from 293 cells using phospho-JUND-S255 antibody and the same antibody preincubated with blocking peptide. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Jun-D pSer255 antibody

Jun-D Rabbit Aff - Purified Hu, Ms, Rt E, IP, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Jun-D pSer255 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JunD (phospho- Ser255) antibody. Rabbit Aff - Purified Hu, Ms P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

Jun-D pSer255 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JunD (phospho- Ser255) antibody. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µl / €240.00
  Acris Antibodies GmbH

Jun-D antibody

Immunohistochemistry analysis of JunD antibody (Cat.-No AP06193PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt E, IP, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Jun-D antibody

Western blot analysis of anti-JUND Antibody in Jurkat cell line lysates (35ug/lane). JUND (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Jun-D antibody

Jun-D Rabbit Purified Hu C, E, EMSA, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Jun-D antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using JUND polyclonal antibody ( Cat # PAB5423 ) . Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Jun-D pSer255 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using JunD (Phospho-Ser255) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, IP, P, WB
50 µg / €205.00
  Assay Biotech

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