Junction plakoglobin antibody

Principal name

Junction plakoglobin antibody

Alternative names for Junction plakoglobin antibody

Desmoplakin-3, Desmoplakin III, Catenin gamma, JUP, CTNNG, DP3

SwissProt ID

P14923 (Human), Q02257 (Mouse), Q6P0K8 (Rat), Q8SPJ1 (Bovin), Q8WNW3 (Pig)

Gene ID

3728 (JUP), 81679 (Jup), 16480

Available reactivities

Chk (Chicken), Hu (Human), Rt (Rat), Ms (Mouse), Bt (Bat), Bov (Bovine), Can (Canine), Hst (Hamster), Mky (Monkey), Op (Opossum), Por (Porcine), Prim (Primate), Rb (Rabbit), Bear, Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat, Guinea Pig

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of Junction plakoglobin antibody

The catenins, α, β and γ, are proteins which bind to the highly conserved,intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherincomplexes play an important role mediating cellular adhesion. α-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. β-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. β-catenin has also been found in complexes with the tumor suppressor protein APC. γ-catenin, also known as plakoglobin, binds with α-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTPμ associates with catenin/cadherin complexes and may regulate complex signaling.

General readings

1 Aberle, H.; Bierkamp, C.; Torchard, D.; Serova, O.; Wagner, T.; Natt, E.; Wirsching, J.; Heidkamper, C.; Montagna, M.; Lynch, H. T.; Lenoir, G. M.; Scherer, G.; Feunteun, J.; Kemler, R. : The human plakoglobin gene localizes on chromosome 17q21 and is subjected to loss of heterozygosity in breast and ovarian cancers. Proc. Nat. Acad. Sci. 92: 6384-6388, 1995.
2. Kolligs, F. T.; Kolligs, B.; Hajra, K. M.; Hu, G.; Tani, M.; Cho, K. R.; Fearon, E. R. : Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. Genes Dev. 14: 1319-1331, 2000

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Junction plakoglobin antibody

Junction plakoglobin Mouse IgG2b PG 5.1 Purified Bov, Chk, Hu, Ms, Rt, Ze C, ICC/IF, IP, P, WB
50 µg / €310.00
  Acris Antibodies GmbH

Junction plakoglobin antibody

Western blot analysis of extracts of various cell lines, using JUP antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Junction plakoglobin antibody

Immunohistochemical analysis of paraffin-embedded rectum tissues using JUP mouse mAb with DAB staining. Mouse IgG1 4C12 Ascites Hu E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

Junction plakoglobin antibody

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 2G9 Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Junction plakoglobin antibody

Immunoperoxidase of monoclonal antibody to JUP on formalin-fixed paraffin-embedded human lymphoma tissue. [antibody concentration 3ug/ml] Mouse IgG 2G9 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Junction plakoglobin antibody

AP15399PU-N Catenin gamma antibody staining of Breast carcinoma Rabbit Purified Hu, Ms, Rt P
0.5 ml / €360.00
  Acris Antibodies GmbH

Junction plakoglobin antibody

AP15399PU-N Catenin gamma antibody staining of Breast carcinoma Rabbit Purified Hu, Ms, Rt P
1 ml / €450.00
  Acris Antibodies GmbH

Junction plakoglobin antibody

AP15399PU-N Catenin gamma antibody staining of Breast carcinoma Rabbit Purified Hu, Ms, Rt P
0.1 ml / €180.00
  Acris Antibodies GmbH

Junction plakoglobin (C-term) antibody

TA302670 staining (0.2µg/ml) of A431 lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Junction plakoglobin antibody

Western blot analysis of extracts from HeLa cells, using Catenin-? antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Junction plakoglobin antibody

Predicted cell location: Cell membrane. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using JUP antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Junction plakoglobin antibody

Predicted band size: 82 kDa . Positive control: A549 and human fetal brain tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: A549 cell lysate Lane2: Human fetal brain tissue lysate Lysates: 50 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Junction plakoglobin antibody

Western blot analysis of JUP Antibody (C-term) (Cat. #TA325089) in MCF-7 cell line lysates (35ug/lane). JUP (arrow) was detected using the purified Pab. Rabbit IgG Purified Bov, Hu, Ms, Por, Rt F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Junction plakoglobin antibody

Western blot analysis on HeLa cell lysate using Catenin-gamma Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Junction plakoglobin antibody

Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-4: Mouse heart tissue, Hela cells, HUVEC cells, mouse skin tissue, Primary antibody: (JUP Antibody) at dilution 1/1150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Junction plakoglobin antibody

Human Breast Carcinoma stained with anti-Catenin-gamma antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Junction plakoglobin antibody

Junction plakoglobin Mouse IgG1 15F11 Purified Hu, Ms, Rt ICC/IF, IP, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Junction plakoglobin antibody

Lane 1: MCF7 Whole Cell Lysate.
Lane 2: HeLa Whole Cell Lysate.
Lane 3: MM231 Whole Cell Lysate.
Lane 4: HT1080 Whole Cell Lysate. Mouse IgG1 CN-3 Aff - Purified Chk, Hu, Rt C, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Junction plakoglobin antibody

Immunohistochemical analysis in paraffin-embedded human breast carcinoma tissue using Catenin-γ / Junction plakoglobin antibody (Cat.-No. AP06039PU-N). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Junction plakoglobin (732-745) antibody

Heart: Formalin-Fixed Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Bt, Can, Elephant, Hst, Hu, Mky, Ms, Op, Por, Prim, Rb, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

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