Junctophilin-2 / JPH2 antibody

Principal name

Junctophilin-2 / JPH2 antibody

Alternative names for Junctophilin-2 / JPH2 antibody

JP2

SwissProt ID

Q2PS20 (Rat), Q9BR39 (Human), Q9ET78 (Mouse), Q9GKY7 (Rabit)

Gene ID

57158 (JPH2), 59091 (Jph2), 296345

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Junctophilin-2 / JPH2 antibody

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH2 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.

General readings

Landstrom,A.P., (2007) J. Mol. Cell. Cardiol. 42 (6), 1026-1035

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Junctophilin-2 / JPH2 (C-term) antibody

  Rabbit Polyclonal JPH2 Antibody  
Western blot analysis of JPH2 in 293 cell lysate with JPH2 antibody at 2 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Junctophilin-2 / JPH2 antibody

  Rabbit Polyclonal JPH2 Antibody  
Western blot analysis of JPH2 in mouse brain tissue lysate with JPH2 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Junctophilin-2 / JPH2 antibody

  Rabbit Polyclonal Anti-JPH2  
WB Suggested Anti-JPH2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Junctophilin-2 / JPH2 antibody

  JPH2 mouse monoclonal antibody, clone OTI1F5 (formerly 1F5)  
Anti-JPH2 mouse monoclonal antibody (TA506941) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY JPH2(RC219661). Mouse IgG1 OTI1F5 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Junctophilin-2 / JPH2 antibody

  JPH2 mouse monoclonal antibody, clone OTI1A1 (formerly 1A1)  
Anti-JPH2 mouse monoclonal antibody (TA506961) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY JPH2(RC219661). Mouse IgG2a OTI1A1 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Junctophilin-2 / JPH2 antibody

  JPH2 mouse monoclonal antibody, clone OTI1E1 (formerly 1E1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY JPH2 (RC219661, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-JPH2. Mouse IgG1 OTI1E1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Junctophilin-2 / JPH2 antibody

  JPH2 mouse monoclonal antibody, clone OTI2E5 (formerly 2E5)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY JPH2 (RC219661, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-JPH2. Mouse IgG2a OTI2E5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Junctophilin-2 / JPH2 antibody

  JPH2 mouse monoclonal antibody, clone OTI2D3 (formerly 2D3)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY JPH2 (RC219661, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-JPH2. Mouse IgG2b OTI2D3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Junctophilin-2 / JPH2 (C-term) antibody

Immunohistochemistry Image: Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

JPH2 - human gene knockout kit via CRISPR

JPH2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

JPH2 - human gene knockout kit via CRISPR

JPH2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

JPH2 - human gene knockout kit via CRISPR

JPH2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

JPH2 - human gene knockout kit via CRISPR

JPH2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jph2 - mouse gene knockout kit via CRISPR

Jph2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Jph2 - mouse gene knockout kit via CRISPR

Jph2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jph2 - mouse gene knockout kit via CRISPR

Jph2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jph2 - mouse gene knockout kit via CRISPR

Jph2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Junctophilin-2 / JPH2 (transcript variant 1)

  Recombinant protein of human junctophilin 2 (JPH2), transcript variant 1  
Junctophilin-2 / JPH2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, JPH2 (mGFP-tagged) - Human junctophilin 2 (JPH2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, JPH2 (mGFP-tagged) - Human junctophilin 2 (JPH2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,560.00
  OriGene Technologies, Inc.

Lenti ORF particles, JPH2 (mGFP-tagged)-Human junctophilin 2 (JPH2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, JPH2 (mGFP-tagged)-Human junctophilin 2 (JPH2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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