Junctophilin-4 / JPH4 antibody

Principal name

Junctophilin-4 / JPH4 antibody

Alternative names for Junctophilin-4 / JPH4 antibody

JPHL1, KIAA1831, JP4

SwissProt ID

Q69FB3 (Rat), Q80WT0 (Mouse), Q96JJ6 (Human)

Gene ID

84502 (JPH4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of Junctophilin-4 / JPH4 antibody

Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Junctophilin-4 / JPH4 antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Junctophilin-4 / JPH4 (C-term) antibody

Western blot analysis of JPH4 in 293 cell lysate with JPH4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Junctophilin-4 / JPH4 (Center) antibody

Western blot analysis of JPH4 in mouse brain tissue lysate with JPH4 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Junctophilin-4 / JPH4 antibody

Host: Rabbit; Target Name: JPH4; Sample Tissue: U937 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Junctophilin-4 / JPH4 Control Peptide

Junctophilin-4 / JPH4
50 µg / €160.00
  Acris Antibodies GmbH

Junctophilin-4 / JPH4 Control Peptide

Junctophilin-4 / JPH4
50 µg / €160.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Junctophilin-4 / JPH4

Junctophilin-4 / JPH4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

JPH4 overexpression lysate

JPH4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Lysates (Overexpressed)

Catalog No.    

JPH4 overexpression lysate

JPH4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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