Junctophilin-4 / JPH4 antibody

Principal name

Junctophilin-4 / JPH4 antibody

Alternative names for Junctophilin-4 / JPH4 antibody

JPHL1, KIAA1831, JP4

SwissProt ID

Q69FB3 (Rat), Q80WT0 (Mouse), Q96JJ6 (Human)

Gene ID

84502 (JPH4), 319984 (Jph4), 445271

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of Junctophilin-4 / JPH4 antibody

Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Junctophilin-4 / JPH4 antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Junctophilin-4 / JPH4 (C-term) antibody

  Rabbit Polyclonal JPH4 Antibody  
Western blot analysis of JPH4 in 293 cell lysate with JPH4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Junctophilin-4 / JPH4 (Center) antibody

  Rabbit Polyclonal JPH4 Antibody  
Western blot analysis of JPH4 in mouse brain tissue lysate with JPH4 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Junctophilin-4 / JPH4 antibody

  Rabbit Polyclonal Anti-JPH4 Antibody  
Host: Rabbit; Target Name: JPH4; Sample Tissue: U937 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

JPH4 - human gene knockout kit via CRISPR

JPH4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

JPH4 - human gene knockout kit via CRISPR

JPH4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

JPH4 - human gene knockout kit via CRISPR

JPH4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

JPH4 - human gene knockout kit via CRISPR

JPH4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jph4 - mouse gene knockout kit via CRISPR

Jph4 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Jph4 - mouse gene knockout kit via CRISPR

Jph4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jph4 - mouse gene knockout kit via CRISPR

Jph4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jph4 - mouse gene knockout kit via CRISPR

Jph4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Junctophilin-4 / JPH4

  Recombinant protein of human junctophilin 4 (JPH4)  
Junctophilin-4 / JPH4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

JPH4 overexpression lysate

JPH4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

JPH4 overexpression lysate

JPH4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Jph4 (GFP-tagged) - Mouse junctophilin 4 (cDNA clone MGC:62430 IMAGE:5689347), 200 uL, >10^7 TU/mL

Lenti ORF particles, Jph4 (GFP-tagged) - Mouse junctophilin 4 (cDNA clone MGC:62430 IMAGE:5689347), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Jph4 (GFP-tagged) - Mouse junctophilin 4 (Jph4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Jph4 (GFP-tagged) - Mouse junctophilin 4 (Jph4), 200 uL, >10^7 TU/mL  
200 µl / €1,280.00
  OriGene Technologies, Inc.

Lenti ORF particles, Jph4 (Myc-DDK-tagged) - Mouse junctophilin 4 (cDNA clone MGC:62430 IMAGE:5689347), 200 uL, >10^7 TU/mL

Lenti ORF particles, Jph4 (Myc-DDK-tagged) - Mouse junctophilin 4 (cDNA clone MGC:62430 IMAGE:5689347), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Jph4 (Myc-DDK-tagged) - Mouse junctophilin 4 (Jph4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Jph4 (Myc-DDK-tagged) - Mouse junctophilin 4 (Jph4), 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Jph4 (GFP-tagged ORF) - Rat junctophilin 4 (Jph4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Jph4 (GFP-tagged ORF) - Rat junctophilin 4 (Jph4), 200 uL, >10^7 TU/mL  
200 µl / €1,290.00
  OriGene Technologies, Inc.

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