KCNA4 antibody

Principal name

KCNA4 antibody

Alternative names for KCNA4 antibody

Potassium voltage-gated channel subfamily A member 4, Voltage-gated potassium channel subunit Kv1.4, HPCN2, HBK4, HUKII, RCK4, RHK1, RK3

SwissProt ID

P15385 (Rat), P22459 (Human), Q05037 (Bovin), Q28527 (Muspf), Q61423 (Mouse)

Gene ID

3739 (KCNA4), 25469 (Kcna4)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of KCNA4 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alphasubunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1-KV4 subfamilies generate functional K+ channels in a homotetrameric configuration (3).

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNA4 antibody

IHC analysis of Kv1.4 using the antibody Mouse IgG1 S13-31 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNA4 antibody

Western blot analysis of rat brain membranes: 1. Anti-KV1.4 antibody , (1:200). 2. Anti-KV1.4 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNA4 antibody

Adult rat hippocampus immunohistochemistry. Mouse IgG1 K13/31 Supernatant Hu, Ms, Rt C, ICC/IF, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCNA4 antibody

Tissue and transfected cell immunoblot: extracts of crude adult rat brain membrane (RBM) and COS cells transiently transfected with untagged Kv1.4 or Kv2.1 plasmid and probed with L71/5 (left), K13/31 (middle) or K89/34 (right) TC supe. Mouse IgG1 L71/5 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCNA4 antibody

Adult rat hippocampus immunohistochemistry. Mouse IgG1 K13/31 Purified Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCNA4 antibody

Tissue and transfected cell immunoblot: extracts of crude adult rat brain membrane (RBM) and COS cells transiently transfected with untagged Kv1.4 or Kv2.1 plasmid and probed with L71/5 (left), K13/31 (middle) or K89/34 (right) TC supe. Mouse IgG1 L71/5 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCNA4 (13-37) antibody

KCNA4 Mouse IgG1 S13-31 Purified Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

KCNA4 antibody

Kv 1.4 potassium channel antibody. A] Postulated structure of rat Kv 1.4 showing the NH2 terminal seq. Used to generate X1037. Western blots of: B] rat hippocampal membrane (90kDa), C] HEK293 cells transfected with Kv 1.4 and D] PSD-95 transfected cells (95 kDa). Rabbit IgG Purified Rt WB
0.1 mg / €360.00
  Acris Antibodies GmbH

KCNA4 antibody

KCNA4 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €360.00
  Acris Antibodies GmbH

KCNA4 antibody

KCNA4 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

KCNA4 antibody

KCNA4 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

KCNA4 antibody

KCNA4 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

KCNA4 antibody

KCNA4 Rabbit Hu, Ms, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

KCNA4 (13-37) antibody

Kv1.4 staining of adult rat hippocampus. Mouse IgG1 Aff - Purified Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 ml / €440.00
  Neuromics Antibodies

KCNA4 antibody

KCNA4 Rabbit Serum Hu, Ms, Rt P, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

KCNA4 antibody

KCNA4 Mouse IgG1 S13-31 Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €450.00
  Novus Biologicals Inc.

KCNA4 antibody

Immunohistochemistry-Paraffin: Kv1.4 Antibody [NBP1-89691] - Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KCNA4

KCNA4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

KCNA4

KCNA4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

19 Item(s)

per page
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