KCNA6 antibody

Principal name

KCNA6 antibody

Alternative names for KCNA6 antibody

Voltage-gated potassium channel subunit Kv1.6, HBK2, Potassium voltage-gated channel subfamily A member 6

SwissProt ID

P17658 (Human), P17659 (Rat), Q61923 (Mouse)

Gene ID

3742 (KCNA6), 16494 (Kcna6), 64358

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of KCNA6 antibody

KV1.6 is a mammalian voltage dependent K+ channel, homologous to the Drosophila Shaker K+ channel. KV1.6 was first cloned from human brain. Eight Shaker related genes exist in mammals constituting the KV1, subfamily of the large KV channel family of genes.A functiol KV1 channel is either a membrane spanning homotetramer or heterotetramer, which is composed of members of the same subfamily. In addition several auxiliary subunits and intracellular proteins might interact with the channel and affect its function.he structure of KV1.6 channel is similar to all KV channels and includes six membrane spanning helixes creating a voltage sensor domain and a pore domain. The channel is expressed in neurons and other supporting cells in the brain, in cardiac and smooth muscle tissue as well as in ovary and testis and its activity influences the membrane potential and excitability of expressing cells.KV1.6 channels are sensitive to low doses of TEA (7 mM) and high doses of 4-AP (1.5 mM), the â??classicalâ? non-selective potassium channel blockers.Several toxins from skes, scorpions and sea anemones venoms are potent blockers (affecting the channels in the nomolar range) of KV1.6 channels. Among these the most potent and selective are a-Dendrotoxin (#D-350), (9-25 nM) and d-Dendrotoxin (#D-380), (23 nM), Agitoxin-2 (#RTA-420), (0.036 nM) Hongotoxin-1 (#RTH-400), (6 nM), Margatoxin (#RTM-325), (5 nM) and Stichodactyla Toxin (#RTS-400), (0.16 mM).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNA6 antibody

IHC analysis of Kv1.6 in frozen sections of mouse brain extract using the antibody Mouse IgG3 S19-36 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNA6 antibody

Western blot analysis of rat brain membranes: 1. Anti-Kv1.6 antibody , (1:200). 2. Anti-Kv1.6 antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNA6 antibody

Immunofluorescence staining transiently Kv1.6-transfected COS cells Mouse IgG3 K19/36 Supernatant Hu, Ms, Rt C, IP
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCNA6 antibody

Immunofluorescence staining transiently Kv1.6-transfected COS cells Mouse IgG3 K19/36 Purified Hu, Ms, Rt C, IP
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCNA6 antibody

KCNA6 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €360.00
  Acris Antibodies GmbH

KCNA6 antibody

KCNA6 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

KCNA6 antibody

KCNA6 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

KCNA6 antibody

KCNA6 Rabbit IgG Hu, Ms, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

KCNA6 antibody

KCNA6 Rabbit Serum Hu, Ms, Rt P, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

KCNA6 antibody

KCNA6 Mouse IgG3 S19-36 Purified Hu, Ms, Rt C, IP, P
0.1 mg / €450.00
  Novus Biologicals Inc.

KCNA6 antibody

Immunohistochemistry-Paraffin: Kv1.6 Antibody [NBP1-89717] - Immunohistochemical staining of human pancreas shows moderate cytoplasmic positivity. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

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