KCNAB1 antibody

Principal name

KCNAB1 antibody

Alternative names for KCNAB1 antibody

Voltage-gated potassium channel subunit beta-1, KCNA1B, Kv-beta-1

SwissProt ID

P63143 (Mouse), P63144 (Rat), Q14722 (Human), Q4PJK1 (Bovin), Q9PWR1 (Chick), Q9XT31 (Rabit)

Gene ID

7881 (KCNAB1), 29737 (Kcnab1)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), Flow Cytometry (F)

Background of KCNAB1 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
Depolarization-activated postassium channels (Kv) play a major role in shaping the electrical signals in the nervous system. KvBeta1.1 is expressed abundantly in rat brain, and is known to induce inactivation of the delayed rectifier channel Kv1.1 and Kv1.4Delta1-110 (3).

General readings

Functional characterization of Kv channel beta-subunits from rat brain. Heinemann SH, Rettig J, Graack HR, Pongs O. J Physiol. 1996 Jun 15;493 ( Pt 3):625-33.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNAB1 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-KCNAB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503966) Mouse IgG1 OTI4E7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-KCNAB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503968) Mouse IgG1 OTI7C7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-KCNAB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA503971) Mouse IgG1 OTI7F12 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

adult rat hippocampus immunohistochemistry Mouse IgG1 K47/42 Supernatant Hu, Ms, Rt C, ICC/IF, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCNAB1 antibody

adult rat hippocampus immunohistochemistry Mouse IgG1 K47/42 Purified Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCNAB1 antibody

IHC analysis of KvBeta 1.2 in frozen sections of mouse brain extract using the antibody Mouse IgG1 S47-42 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNAB1 antibody

IHC analysis of KvBeta1.1 tested on mouse brain using the antibody Mouse IgG2b S9-40 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNAB1 antibody

IHC analysis of Pan-Kv Beta in frozen sections of mouse brain extract using the antibody Mouse IgG2a S40-17 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNAB1 antibody

Western blot analysis of human SH-SY5Y neuroblastoma cell lysate (lanes 1 and 4), mouse brain lysate (lanes 2 and 5) and rat brain lysate (lanes 3 and 6): 1-3. Anti- KVβ1 antibody , (1:200). 4-6. Anti- KVβ1 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNAB1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KCNAB1 (RC207384, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KCNAB1. Mouse IgG1 OTI3G3 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KCNAB1 (RC207384, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KCNAB1. Mouse IgG1 OTI1C2 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KCNAB1 (RC207384, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KCNAB1. Mouse IgG1 OTI9C9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KCNAB1 (RC207384, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KCNAB1. Mouse IgG1 OTI2A8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-KCNAB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503967) Mouse IgG1 OTI9F7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KCNAB1 (RC207384, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KCNAB1. Mouse IgG1 OTI6E5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

Anti-KCNAB1 mouse monoclonal antibody (TA503970) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY KCNAB1(RC207384). Mouse IgG1 OTI2F1 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNAB1 antibody

Immunoblot on adult rat brain membrane (RBM) and lysates from Kvβ1.1 -transfected (COS+) and untransfected (COS-) COS cells Mouse IgG2b K9/40 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCNAB1 antibody

Immunoblot on adult rat brain membrane (RBM) and lysates from Kvβ1.1 -transfected (COS+) and untransfected (COS-) COS cells Mouse IgG2b K9/40 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCNAB1 (7-28) antibody

KCNAB1 Mouse IgG2b S9-40 Purified Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

KCNAB1 antibody

KCNAB1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Items 1 to 20 of 34 total

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