KCND3 antibody

Principal name

KCND3 antibody

Alternative names for KCND3 antibody

Potassium voltage-gated channel subfamily D member 3, Voltage-gated potassium channel subunit Kv4.3

SwissProt ID

Q62897 (Rat), Q9TTT5 (Rabit), Q9UK17 (Human), Q9Z0V1 (Mouse)

Gene ID

3752 (KCND3), 65195 (Kcnd3), 56543

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Chk (Chicken), African clawed frog, Xen (Xenopus), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of KCND3 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligand- gated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels. Potassium volgate-gated channel subfamily D member 3 (also knowns as Kv4.3) is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current, the main contributing current to the repolarizing phase 1 of the cardiac action potential.

General readings

Hatano,N., et al., (2004) J. Biol. Chem. 279 (7), 5450-5459

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCND3 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 K75/41 Supernatant Hu, Ms, Rt, Xen C, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCND3 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 K75/41 Purified Hu, Ms, Rt, Xen C, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCND3 antibody

Western blot analysis of Kv4.3 on rat brain membrane tissues using a 1:1000 dilution of the antibody Mouse IgG1 S75-41 Purified Hu, Ms, Rt, Xen C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCND3 antibody

Western blot analysis of rat brain membranes: 1. Anti-Kv4.3 antibody, (1:200). 2. Anti-Kv4.3 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCND3 antibody

WB Suggested Anti-KCND3 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCND3 antibody

WB Suggested Anti-KCND3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCND3 (415-636) antibody

Immunohistochemistry analysis of Kv4.3 using AM20105PU-N (Clone S75-41) tested on mouse cerebellum. Neurons appear to be positive on the membrane and slightly in the cytoplasm. Positivity on the fibers as well. Negative white matter. Mouse IgG1 S75-41 Purified Hu, Ms, Rt, Xen C, ICC/IF, IP, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

KCND3 antibody

KCND3 Rabbit Purified Hu C, E, ICC/IF, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

KCND3 antibody

KCND3 Rabbit Serum Hu
0.2 ml / €400.00
  Acris Antibodies GmbH

KCND3 (55-64) antibody

Western blot analysis of extracts from mouse brain using anti-KV4.3 rabbit whole antiserum. Rabbit Azide Free Ms E, WB
0.5 mg / €680.00
  Acris Antibodies GmbH

KCND3 (55-64) antibody

Western blot analysis of extracts from mouse brain using anti-KV4.3 rabbit whole antiserum. Rabbit Azide Free Ms E, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

KCND3 antibody

KCND3 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

KCND3 antibody

Human HepG2; WB Suggested Anti-KCND3 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:12500. Positive Control: HepG2 cell lysate; KCND3 antibody - middle region (ARP35165_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Por, Rb, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

KCND3 antibody

Human HepG2; WB Suggested Anti-KCND3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: HepG2 cell lysate; KCND3 antibody - middle region (ARP35467_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Chk, Hu, Ms, Por, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

KCND3 antibody

KCND3 Mouse IgG2a S75-41 Purified Hu, Ms, Rt, Xen IP, P, WB
0.1 mg / €450.00
  Novus Biologicals Inc.

KCND3 antibody

Immunohistochemistry-Paraffin: Kv4.3 Antibody [NBP1-82864] - Immunohistochemical staining of human pancreas shows moderate positivity in indercalated ducts in exocrine pancreas. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

KCND3 overexpression lysate

KCND3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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