KCND3 antibody

Principal name

KCND3 antibody

Alternative names for KCND3 antibody

Potassium voltage-gated channel subfamily D member 3, Voltage-gated potassium channel subunit Kv4.3

SwissProt ID

Q62897 (Rat), Q9TTT5 (Rabit), Q9UK17 (Human), Q9Z0V1 (Mouse)

Gene ID

3752 (KCND3), 65195 (Kcnd3), 56543

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Chk (Chicken), African clawed frog, Xen (Xenopus), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of KCND3 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligand- gated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels. Potassium volgate-gated channel subfamily D member 3 (also knowns as Kv4.3) is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current, the main contributing current to the repolarizing phase 1 of the cardiac action potential.

General readings

Hatano,N., et al., (2004) J. Biol. Chem. 279 (7), 5450-5459

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCND3 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 K75/41 Supernatant Hu, Ms, Rt, Xen C, IP, WB
5 ml / €460.00
  Antibodies Incorporated

NeuroMab

KCND3 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG1 K75/41 Purified Hu, Ms, Rt, Xen C, IP, WB
0.1 ml / €540.00
  Antibodies Incorporated

NeuroMab

KCND3 antibody

  Mouse Monoclonal Anti-Kv4.3 Antibody  
Western blot analysis of Kv4.3 on rat brain membrane tissues using a 1:1000 dilution of the antibody Mouse IgG1 S75-41 Purified Hu, Ms, Rt, Xen C, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCND3 antibody

  Rabbit Polyclonal Anti-KV4.3  
Western blot analysis of rat brain membranes: 1. Anti-Kv4.3 antibody, (1:200). 2. Anti-Kv4.3 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCND3 antibody

  Rabbit Polyclonal Anti-KCND3 Antibody  
WB Suggested Anti-KCND3 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCND3 antibody

  Rabbit Polyclonal Anti-KCND3 Antibody  
WB Suggested Anti-KCND3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCND3 antibody

KCND3 Rabbit Purified Hu C, E, ICC/IF, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

KCND3 antibody

KCND3 Rabbit Serum Hu
0.2 ml / €400.00
  Acris Antibodies GmbH

KCND3 (55-64) antibody

Western blot analysis of extracts from mouse brain using anti-KV4.3 rabbit whole antiserum. Rabbit Azide Free Ms E, WB
0.5 mg / €720.00
  Acris Antibodies GmbH

KCND3 (55-64) antibody

Western blot analysis of extracts from mouse brain using anti-KV4.3 rabbit whole antiserum. Rabbit Azide Free Ms E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

KCND3 - human gene knockout kit via CRISPR

KCND3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KCND3 - human gene knockout kit via CRISPR

KCND3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCND3 - human gene knockout kit via CRISPR

KCND3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCND3 - human gene knockout kit via CRISPR

KCND3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kcnd3 - mouse gene knockout kit via CRISPR

Kcnd3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Kcnd3 - mouse gene knockout kit via CRISPR

Kcnd3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kcnd3 - mouse gene knockout kit via CRISPR

Kcnd3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kcnd3 - mouse gene knockout kit via CRISPR

Kcnd3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

KCND3 overexpression lysate

KCND3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KCND3 (mGFP-tagged) - Human potassium voltage-gated channel, Shal-related subfamily, member 3 (KCND3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, KCND3 (mGFP-tagged) - Human potassium voltage-gated channel, Shal-related subfamily, member 3 (KCND3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

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