KCNE3 antibody

Principal name

KCNE3 antibody

Alternative names for KCNE3 antibody

KCNE3, Potassium channel subunit beta MiRP2, MinK-related peptide 2, Potassium voltage-gated channel subfamily E member 3, Minimum potassium ion channel-related peptide 2

SwissProt ID

Q9JJV7 (Rat), Q9WTW2 (Mouse), Q9Y6H6 (Human)

Gene ID

10008 (KCNE3), 57442 (Kcne3), 63883

Available reactivities

Hst (Hamster), Hu (Human), Mky (Monkey), Gorilla, Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Xen (Xenopus)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of KCNE3 antibody

KCNE3 (or MiRP2) is a member of a family of proteins that regulate the activity of voltage-dependent K+ channels. The other members of the family are KCNE1 (IsK, MiNK), KCNE2 (MiRP1), KCNE4 (MiRP3) and KCNE5 (MiRP4). KCNE1 is the founding member of the family and was initially believed to form a K+ channel itself, but was latter recognized that it worked as a regulatory b subunit associated with the Kv7.1 (KCNQ1) a protein. KCNE3 was discovered based on its homology with KCNE1. The KCNE regulatory subunits are small proteins (14- 20 kD) with a type-1 integral membrane topology. It is believed that both the cytoplasmic C-terminus tail and the transmembrane domain are necessary for the interaction with the a subunits. The stoichiometry of the KCNE subunits with their partner a subunits in the tive channels is not clear and ratios ranging from 2 to 14 KCNE subunits per 4 a subunits have been proposed. KCNE3 is relatively widely expressed in several tissues with prominent expression in the kidney and skeletal muscle. KCNE3 is quite promiscuous and associations with Kv7.1, Kv3.4, Kv7.4 (KCNQ4), Kv11.1 (HERG), Kv2.1 and Kv3.1b have been demonstrated. The best characterized interactions are with the former two proteins. KCNE3 interacts with Kv7.1 in epithelial cells of the gastrointestil tract where it appears to be important for + absorption. In skeletal muscle KCNE3 couples to Kv3.4 to regulate muscle function. Indeed, a mutation in KCNE3 (R83H) has been associated with an inherited form of periodic paralysis (Thyrotoxic hypokalemic periodic paralysis).

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNE3 antibody

  KCNE3 Rabbit Polyclonal (Internal) Antibody  
Anti-KCNE3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Gorilla, Hst, Hu, Mky
50 µg / €345.00
  OriGene Technologies, Inc.

KCNE3 antibody

  KCNE3 Rabbit Polyclonal (Internal) Antibody  
Anti-KCNE3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Bov, Can, Chk, Eq, Gorilla, Hst, Hu, Mky, Ms, Por, Rb, Rt, Xen
50 µg / €345.00
  OriGene Technologies, Inc.

KCNE3 antibody

  Rabbit Polyclonal Anti-KCNE3  
Western blot analysis of rat kidney (lanes 1 and 3) and rat heart (lanes 2 and 4) membranes: 1, 2. Anti-KCNE3 (MiRP2) antibody, (1:200). 3, 4. Anti-KCNE3 (MiRP2) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

Kcne3 - mouse gene knockout kit via CRISPR

Kcne3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Kcne3 - mouse gene knockout kit via CRISPR

Kcne3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kcne3 - mouse gene knockout kit via CRISPR

Kcne3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kcne3 - mouse gene knockout kit via CRISPR

Kcne3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KCNE3 (mGFP-tagged) - Human potassium voltage-gated channel, Isk-related family, member 3 (KCNE3), 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNE3 (mGFP-tagged) - Human potassium voltage-gated channel, Isk-related family, member 3 (KCNE3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, KCNE3 (Myc-DDK tagged) - Human potassium voltage-gated channel, Isk-related family, member 3 (KCNE3) , 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNE3 (Myc-DDK tagged) - Human potassium voltage-gated channel, Isk-related family, member 3 (KCNE3) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcne3 (GFP-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (GFP-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcne3 (GFP-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (GFP-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcne3 (GFP-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (GFP-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcne3 (GFP-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (GFP-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcne3 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcne3 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcne3 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcne3 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (Myc-DDK-tagged) - Mouse potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcne3 (GFP-tagged ORF) - Rat potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (GFP-tagged ORF) - Rat potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcne3 (Myc-DDK-tagged ORF) - Rat potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcne3 (Myc-DDK-tagged ORF) - Rat potassium voltage-gated channel, Isk-related subfamily, gene 3 (Kcne3), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

19 Item(s)

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