KCNH6 antibody

Principal name

KCNH6 antibody

Alternative names for KCNH6 antibody

KCNH6, ERG2, HERG2, Eag-related protein 2, Kv11.2, Voltage-gated potassium channel subunit Kv11.2, Ether-a-go-go-related gene potassium channel 2, Potassium voltage-gated channel subfamily H member 6, Ether-a-go-go-related protein 2

SwissProt ID

O54853 (Rat), Q9H252 (Human)

Gene ID

81033 (KCNH6)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Chk (Chicken), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of KCNH6 antibody

Kv11.2 (erg2) is a member of the ether-a-go-go (EAG) subfamily of voltage-dependent K+ channels. The erg subfamily includes the closely related proteins Kv11.1 (erg1) and Kv11.3 (erg3) that possess the sigture structure of the voltage-dependent K+ channels: six membrane-spanning domains with intracellular N and C termini. As with all voltage-dependent K+ channels, the functiol channel is a tetramer composed of four subunits. It has been suggested that the Kv11 subfamily members can form functiol heteromultimers within the subfamily. Kv11.2 produces currents characterized by strong inward rectification with slow activation and very rapid ictivation kinetics, which closely resemble those produced by the much studied channel Kv11.1. The expression of Kv11.2 seems to be limited to the brain and the pituitary gland. The same is true for the Kv11.3 protein, while Kv11.1 is more widely expressed. From a pharmacological point of view, Kv11.2 channels can be blocked by well characterized organic blockers such as the anti-arrhythmic drug E-4031. In addition, the peptide toxins Ergtoxin-1 and BeKm-1 , block Kv11.2 with different potencies.

General readings

Bauer,C.K., et al., (2003) Pflugers Arch. 445 (5), 589-600

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNH6 antibody

  Rabbit Polyclonal Anti-KV11.2 (erg2)  
Western blot analysis of rat brain (1 and 3) and rat cortex ( 2 and 4) lysate: 1, 2. Anti-Kv11.2 (erg2) antibody, (1:200). 3, 4. Anti-Kv11.2 (erg2) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNH6 antibody

  Rabbit Polyclonal Anti-KCNH6 Antibody  
WB Suggested Anti-KCNH6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCNH6 antibody

  Rabbit Polyclonal Anti-KCNH6 Antibody  
WB Suggested Anti-KCNH6 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNH6 antibody

  Rabbit Polyclonal Anti-KCNH6 Antibody  
WB Suggested Anti-KCNH6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCNH6 antibody

  Rabbit Polyclonal Anti-KCNH6 Antibody  
WB Suggested Anti-KCNH6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: NCI-H226 cell lysate KCNH6 is strongly supported by BioGPS gene expression data to be expressed in NCI-H226 Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCNH6 antibody

  Rabbit Polyclonal Anti-KCNH6 Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hepg2 cells, HT29 cells, Primary antibody: (KCNH6 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds Rabbit IgG Purified Hu, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

KCNH6 - human gene knockout kit via CRISPR

KCNH6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KCNH6 - human gene knockout kit via CRISPR

KCNH6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCNH6 - human gene knockout kit via CRISPR

KCNH6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCNH6 - human gene knockout kit via CRISPR

KCNH6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

KCNH6 overexpression lysate

KCNH6 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KCNH6 (mGFP-tagged)-Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNH6 (mGFP-tagged)-Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,030.00
  OriGene Technologies, Inc.

Lenti ORF particles, KCNH6 (mGFP-tagged) - Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNH6 (mGFP-tagged) - Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,890.00
  OriGene Technologies, Inc.

Lenti ORF particles, KCNH6 (Myc-DDK-tagged)-Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNH6 (Myc-DDK-tagged)-Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,830.00
  OriGene Technologies, Inc.

Lenti ORF particles, KCNH6 (Myc-DDK tagged) - Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNH6 (Myc-DDK tagged) - Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,700.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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