KCNJ13 antibody

Principal name

KCNJ13 antibody

Alternative names for KCNJ13 antibody

Inward rectifier K(+) channel Kir7.1, Inward rectifier potassium channel 13, Potassium channel inwardly rectifying subfamily J member 13

SwissProt ID

O60928 (Human), O70617 (Rat), P86046 (Mouse), Q9QZ65 (Cavpo)

Gene ID

3769 (KCNJ13), 94341 (Kcnj13)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of KCNJ13 antibody

FUNCTION: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.; Tissue specificity: Predominantly expressed in small intestine. Expression is also detected in stomach, kidney, and all central nervous system regions tested with the exception of spinal cord.; Subcellular location: Membrane, Multi-pass membrane protein.; Involvement in disease: Defects in KCNJ13 are the cause of snowflake vitreoretinal degeneration (SVD). SVD is a developmental and progressive hereditary eye disorder that affects multiple tissues within the eye. Diagnostic features of SVD include fibrillar degeneration of the vitreous humor, early-onset cataract, minute crystalline deposits in the neurosensory retina, and retinal detachment.

General readings

Zhang, W., et al. Biochem. Biophys. Res. Commun. 377(3):981-986(2008)
Ji, W., et al. Nat. Genet. 40(5):592-599(2008)
Hughes, B.A., et al. Am. J. Physiol., Cell Physiol. 294 (2), C423-C431 (2008)
Hejtmancik, J.F., et al. Am. J. Hum. Genet. 82(1):174-180(2008)
Yang, D., et al. Exp. Eye Res. 86(1):81-91(2008)

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNJ13 antibody

Western blot analysis of rat brain membrane (lanes 1 and 4), mouse brain (lanes 2 and 5) and mouse kidney lysates (lanes 3 and 6): 1-3. Anti-Kir7.1 (extracellular) antibody , (1:200). 4-6. Anti-Kir7.1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNJ13 (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue reacted with KCNJ13 Antibody (N-term) Cat.-No AP52310PU-N, which was peroxidase conjugated to the secondary antibody and  followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

KCNJ13 antibody

KCNJ13 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.


Catalog No.    

KCNJ13 overexpression lysate

KCNJ13 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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