KCNJ2 antibody

Principal name

KCNJ2 antibody

Alternative names for KCNJ2 antibody

KCNJ2, HIRK1, Inward rectifier K(+) channel Kir2.1, Cardiac inward rectifier potassium channel, IRK1, Inward rectifier potassium channel 2, Potassium channel, inwardly rectifying subfamily J member 2

SwissProt ID

O19182 (Bovin), P35561 (Mouse), P63252 (Human), Q64273 (Rat)

Gene ID

3759 (KCNJ2), 16518 (Kcnj2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine)

Available hosts

Mouse, Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of KCNJ2 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics.
The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
The Kir2.1 inward-rectifier potassium ion channel is encoded by the KCNJ2 gene. A defect in this gene is associated with Andersen-Tawil syndrome (3).

General readings

Hinard V. et al. Initiation of human myoblast differentiation via dephosphorylation of Kir2.1 K+ channels at tyrosine 242. Development, Mar 2008; 135: 859 – 867.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNJ2 antibody

Western blot analysis of Kir2.1 in COS transient cells using a 1:1000 dilution of the antibody Mouse IgG1 S21-32 Purified Hu, Ms, Rt C, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNJ2 antibody

Western blot analysis of rat heart (1 and 3) and rat brain (2 and 4) membranes: 1, 2. Anti-Kir2.1 antibody , (1:200). 3, 4. Anti-Kir2.1, antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNJ2 antibody

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with HA-tagged Kir2.1 or untagged Kv2.1 plasmids and probed with N112B/14 (left) and K89/41 (right) TC supe. Mouse IgG1 N112B/14 Supernatant Ms, Rt ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCNJ2 antibody

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with HA-tagged Kir2.1 or untagged Kv2.1 plasmids and probed with N112B/14 (left) and K89/41 (right) TC supe. Mouse IgG1 N112B/14 Purified Ms, Rt ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCNJ2 (C-term) antibody

(LEFT) Western blot analysis of KCNJ2 Antibody (C-term) (AP17516PU-N) in NCI-H460 cell line lysates (35ug/lane). KCNJ2 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of KCNJ2 Antibody (C-term) (AP17516PU-N) in mouse lung tissue lysates (35ug/lane). KCNJ2 (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

KCNJ2 antibody

KCNJ2 Chicken Purified Hu C, E, WB
50 µg / €300.00
  Acris Antibodies GmbH

KCNJ2 antibody

KCNJ2 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

KCNJ2 antibody

KCNJ2 polyclonal antibody (A01), Lot # 051011JC01. Western Blot analysis of KCNJ2 expression in Daoy. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

KCNJ2 antibody

KCNJ2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

KCNJ2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNJ2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, P
50 µg / €205.00
  Assay Biotech

KCNJ2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNJ2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, P
0.1 mg / €310.00
  Assay Biotech

KCNJ2 antibody

Western blot analysis of Kir2.1 expression in HeLa (A); mouse brain (B); rat kidney (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

KCNJ2 antibody

Western blot analysis of Kir2.1 expression in HeLa (A); mouse brain (B); rat kidney (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

KCNJ2 antibody

Western blot analysis of Kir2.1 expression in HeLa (A); mouse brain (B); rat kidney (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

KCNJ2 (390-411) antibody

Image: Kir2.1 staining of adult rat hippocampus. Mouse IgG1 Aff - Purified Ms, Rt ICC/IF, WB
0.1 ml / €440.00
  Neuromics Antibodies

KCNJ2 antibody

KCNJ2 Rabbit IgG Aff - Purified Hu, Rt E, P
0.1 mg / €360.00
  Novus Biologicals Inc.

KCNJ2 antibody

KCNJ2 Rabbit IgG Aff - Purified Hu, Rt E, P
50 µg / €290.00
  Novus Biologicals Inc.

KCNJ2 antibody

Immunohistochemistry-Paraffin: Kir2.1 Antibody [NBP1-87709] Immunohistochemical staining of human colon shows strong cytoplasmic and membrane positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KCNJ2

KCNJ2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

KCNJ2

KCNJ2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

20 Item(s)

per page
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