KCNJ3 antibody

Principal name

KCNJ3 antibody

Alternative names for KCNJ3 antibody

GIRK1, Potassium channel, inwardly rectifying subfamily J member 3, G protein-activated inward rectifier potassium channel 1, Inward rectifier K(+) channel Kir3.1

SwissProt ID

P48549 (Human), P63250 (Mouse), P63251 (Rat), Q90854 (Chick)

Gene ID

3760 (KCNJ3), 16519 (Kcnj3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Frozen Sections (C), Flow Cytometry (F)

Background of KCNJ3 antibody

Kir3.1 (or G-protein regulated Inward-Rectifier K+ channel, GIRK1) is a member of the family of inward rectifying K+ channels. The family includes 15 members that are structurally and functiolly different from the voltage-dependent K+ channels. The family’s topology consists of two transmembrane domains that flank a single and highly conserved pore region with intracellular N- and C-termini. As is the case for the voltage-dependent K+ channels the functiol unit for the Kir channels is composed of four subunit that can assembly as either homo or heterotetramers. Kir channels are characterized by a K+ efflux that is limited by depolarizing membrane potentials thus making them essential for controlling resting membrane potential and K+ homeostasis. Kir3.1 is a member of the Kir3.x subfamily that includes four members (Kir3.1- Kir3.4). The Kir3 family is characterized by the fact that the channels can be activated by neurotransmitters and other factors acting via the activation of G-protein coupled receptors. Binding of the corresponding ligand to the G-protein receptor induces the dissociation of Gα-GTP from the Gβγ dimer. The latter directly binds to Kir3 and activates the channel. In the heart, Kir3.1 co-assembles with Kir3.4 to form the prototypical muscarinic-gated K+ channel KAch current, responsible for slowing the heart rate in response of parasympathetic stimulation. In the brain, Kir3.1 co-assembles with Kir3.2 and mediates the inhibitory effects of many neurotransmitters including opioid, adrenergic, muscarinic, dopaminergic and γ-aminobutyric acid (GABA). A peptide toxin origiting from the Apis mellifera bee venom, Tertiapin (#STT-250) was shown to be a potent blocker of Kir3.1 containing channels (8.6 nM for the Kir3.1/3.4 combition and 5.4 nM for the Kir3.1/3.2).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNJ3 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-KCNJ3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504152) Mouse IgG2b OTI3E11 Purified Hu, Mky, Ms F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

KCNJ3 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-KCNJ3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504197) Mouse IgG1 OTI1G3 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNJ3 antibody

Anti-KCNJ3 mouse monoclonal antibody (TA504198) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY KCNJ3(RC205322). Mouse IgG1 OTI1G2 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNJ3 antibody

Anti-KCNJ3 mouse monoclonal antibody (TA504210) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY KCNJ3(RC205322). Mouse IgG1 OTI2E4 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNJ3 antibody

Sample (30 ug of whole cell lysate). A:A431 . B: H1299. C: Hela. 7.5% SDS PAGE. TA308050 diluted at 1:1000. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

KCNJ3 antibody

Western blot analysis of rat brain membranes: 1. Anti-Kir3.1 (GIRK1) antibody , (1:200). 2. Anti-Kir3.1 (GIRK1) antibody, preincubated with the control antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNJ3 antibody

Anti-KCNJ3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

KCNJ3 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KCNJ3 (RC205322, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KCNJ3. Mouse IgG1 OTI2F2 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNJ3 antibody

Anti-KCNJ3 mouse monoclonal antibody (TA504138) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY KCNJ3(RC205322). Mouse IgG2b OTI1C5 Purified Can, Hu, Mky, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNJ3 antibody

Anti-KCNJ3 mouse monoclonal antibody (TA504139) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY KCNJ3(RC205322). Mouse IgG2b OTI1D3 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNJ3 antibody

Anti-KCNJ3 mouse monoclonal antibody (TA504193) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY KCNJ3(RC205322). Mouse IgG1 OTI1B1 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

KCNJ3 antibody

Western blot analysis of KIR3.1 antibody (Cat.-No AP20232PU-N) in extracts from NIH/3T3 cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

KCNJ3 antibody

KCNJ3 Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

KCNJ3 antibody

KCNJ3 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

KCNJ3 pSer185 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using GIRK1/KIR3.1/KCNJ3 (Phospho-Ser185) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

KCNJ3 pSer185 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using GIRK1/KIR3.1/KCNJ3 (Phospho-Ser185) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

KCNJ3 antibody

Immunofluorescence analysis of HeLa cells, using GIRK1/KIR3.1/KCNJ3 (Ab-185) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

KCNJ3 antibody

Immunofluorescence analysis of HeLa cells, using GIRK1/KIR3.1/KCNJ3 (Ab-185) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

KCNJ3 (C-term) antibody

Mouse Kidney; WB Suggested Anti-Kcnj3 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Kidney; Kcnj3 antibody - C-terminal region (ARP35081_P050) in Mouse Kidney cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

KCNJ3 antibody

Immunohistochemistry: Kir3.1 Antibody [NBP1-32958] - Immunohistochemical analysis of Kir3.1 on paraffin-embedded DU145 xenograft, using NBP1-32958. Rabbit IgG Hu P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

20 Item(s)

per page
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