KCNJ4 antibody

Principal name

KCNJ4 antibody

Alternative names for KCNJ4 antibody

KCNJ4, Inward rectifier K(+) channel Kir2.3, Hippocampal inward rectifier, HIRK2, HRK1, HIR, Inward rectifier potassium channel 4, Potassium channel, inwardly rectifying subfamily J member 4

SwissProt ID

P48050 (Human), P52189, P52190, Q64198

Gene ID

3761 (KCNJ4), 116649 (Kcnj4)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of KCNJ4 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene (3-5).

General readings

Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010)
Yan, X., et al. J. Mol. Biol. 392(4):967-976(2009)
He, Y., et al. FEBS Lett. 582(15):2338-2342(2008)
Ji, W., et al. Nat. Genet. 40(5):592-599(2008)
Ureche, O.N., et al. Cell. Physiol. Biochem. 21 (5-6), 347-356 (2008)

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNJ4 antibody

  Mouse Monoclonal anti-KCNJ12 Antibody  
Western blot analysis of Kir2.2 in a human cell line mix using a 1:1000 dilution of TA309413. Mouse IgG1 S124B-38 Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNJ4 antibody

  Rabbit polyclonal anti-KCNJ4 antibody  
Western blot analysis of extracts from 293 cells and NIH/3T3 cells, using KCNJ4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

KCNJ4 antibody

  Mouse monoclonal Kir2.3 Antibody  
Western blot analysis of Kir2.3 in a human cell line mix using a 1:1000 dilution of the antibody Mouse IgG1 S25-35 Purified Hu, Ms, Rt C, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNJ4 antibody

  Rabbit polyclonal Anti-Kir2.3  
Western blot analysis of rat kidney (1,3) and rat brain (2,4) membranes: 1, 2. Anti-Kir2.3 antibody , (1:200) 3, 4. Anti-Kir2.3, antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNJ4 antibody

  Rabbit Polyclonal Anti-KCNJ4 Antibody  
WB Suggested Anti-KCNJ4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 293T cell lysate KCNJ4 is supported by BioGPS gene expression data to be expressed in HEK293T Rabbit IgG Purified Can, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCNJ4 antibody

Adult rat brain immunohistochemistry Mouse IgG1 N25/35 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCNJ4 antibody

Adult rat brain immunohistochemistry Mouse IgG1 N25/35 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCNJ4 (N-term) antibody

Western blot analysis of KCNJ4 Antibody (N-term) Cat.-No AP52311PU-N in CEM cell line lysates (35ug/lane). This demonstrates the KCNJ4 antibody detected the KCNJ4 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

KCNJ4 - human gene knockout kit via CRISPR

KCNJ4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KCNJ4 - human gene knockout kit via CRISPR

KCNJ4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCNJ4 - human gene knockout kit via CRISPR

KCNJ4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCNJ4 - human gene knockout kit via CRISPR

KCNJ4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KCNJ4 (mGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNJ4 (mGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, KCNJ4 (mGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNJ4 (mGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, KCNJ4 (Myc-DDK tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNJ4 (Myc-DDK tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, KCNJ4 (Myc-DDK tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNJ4 (Myc-DDK tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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