KCNJ4 antibody

Principal name

KCNJ4 antibody

Alternative names for KCNJ4 antibody

KCNJ4, Inward rectifier K(+) channel Kir2.3, Hippocampal inward rectifier, HIRK2, HRK1, HIR, Inward rectifier potassium channel 4, Potassium channel, inwardly rectifying subfamily J member 4

SwissProt ID

P48050 (Human), P52189, P52190, Q64198

Gene ID

3761 (KCNJ4), 116649 (Kcnj4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of KCNJ4 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene (3-5).

General readings

Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010)
Yan, X., et al. J. Mol. Biol. 392(4):967-976(2009)
He, Y., et al. FEBS Lett. 582(15):2338-2342(2008)
Ji, W., et al. Nat. Genet. 40(5):592-599(2008)
Ureche, O.N., et al. Cell. Physiol. Biochem. 21 (5-6), 347-356 (2008)

12 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNJ4 antibody

Western blot analysis of Kir2.2 in a human cell line mix using a 1:1000 dilution of TA309413. Mouse IgG1 S124B-38 Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNJ4 antibody

Western blot analysis of extracts from 293 cells and NIH/3T3 cells, using KCNJ4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

KCNJ4 antibody

Western blot analysis of Kir2.3 in a human cell line mix using a 1:1000 dilution of the antibody Mouse IgG1 S25-35 Purified Hu, Ms, Rt C, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNJ4 antibody

Western blot analysis of rat kidney (1,3) and rat brain (2,4) membranes: 1, 2. Anti-Kir2.3 antibody , (1:200) 3, 4. Anti-Kir2.3, antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNJ4 antibody

WB Suggested Anti-KCNJ4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 293T cell lysate KCNJ4 is supported by BioGPS gene expression data to be expressed in HEK293T Rabbit IgG Purified Can, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCNJ4 antibody

Adult rat brain immunohistochemistry Mouse IgG1 N25/35 Supernatant Hu, Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCNJ4 antibody

Adult rat brain immunohistochemistry Mouse IgG1 N25/35 Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCNJ4 (N-term) antibody

Western blot analysis of KCNJ4 Antibody (N-term) Cat.-No AP52311PU-N in CEM cell line lysates (35ug/lane). This demonstrates the KCNJ4 antibody detected the KCNJ4 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

KCNJ4 antibody

Human 293T; WB Suggested Anti-KCNJ4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 293T cell lysate. KCNJ4 is supported by BioGPS gene expression data to be expressed in HEK293T.; KCNJ4 antibody - middle region (ARP35167_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

KCNJ4 antibody

KCNJ4 Rabbit Serum Hu C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

KCNJ4 antibody

Immunohistochemistry-Paraffin: KIR2.3 Antibody [NBP1-92057] - Immunohistochemistry-Paraffin: KIR2.3 Antibody [NBP1-92057] Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KCNJ4

KCNJ4 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

12 Item(s)

per page
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