KCNJ8 antibody

Principal name

KCNJ8 antibody

Alternative names for KCNJ8 antibody

Kir6.1, uKATP-1, ATP-sensitive inward rectifier potassium channel 8, Potassium channel inwardly rectifying subfamily J member 8

SwissProt ID

P97794 (Mouse), Q15842 (Human), Q63664 (Rat)

Gene ID

3764 (KCNJ8), 25472 (Kcnj8), 16523

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of KCNJ8 antibody

Kir 6.1 is a member of the inward rectifier K+ channels (Kir channels), a large family of voltage-independent K+ channels largely involved in stabilization of the membrane resting potential and in K+ transport across membranes. Kir 6.1 like its close relative Kir 6.2 is highly sensitive to inhibition by intracellular ATP. Closure of the channel leads to membrane depolarization hence coupling intracellular metabolism to cellular excitability. Kir 6.1 presents the common topology of the inward-rectifier superfamily: two transmembrane domains flanking a highly conserved pore region with the N and C-terminus located intracellularly. The functiol ATP sensitive channel (KATP) is composed of octamers of four Kir 6.x subunits and four members of the sulfonylurea receptor family SUR1, SUR2A and SUR2B. Kir 6.1 tissue distribution is relatively broad with expression detected in heart, brain, and smooth muscle. We are pleased to introduce an antibody against a highly specific region in the C-termil intracellular domain of the rat Kir 6.1 subunit. Anti-Kir 6.1 antibody (#APC-105) should also recognize Kir 6.1 from human, mouse, pig and rabbit origin.

General readings

Medeiros-Domingo, A., et al. Heart Rhythm 7(10):1466-1471(2010)
Ellis, J.A., et al. Physiol. Genomics 40(3):184-188(2010)
Shi, W., et al. J. Biol. Chem. 285(5):3021-3029(2010)
Winkler, M., et al. J. Biol. Chem. 284(11):6752-6762(2009)
Ploug, K.B., et al. Eur. J. Pharmacol. 601 (1-3), 43-49 (2008)

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNJ8 antibody

  Rabbit polyclonal Anti-Kir6.1  
Western blot analysis of rat heart membranes: 1. Anti-Kir6.1 antibody , (1:200). 2. Anti-Kir6.1 antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNJ8 antibody

  Rabbit Polyclonal Anti-KCNJ8 Antibody  
WB Suggested Anti-KCNJ8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCNJ8 antibody

Left: immunoblot against extracts of COS cells transiently transfected with Myc-tagged Kir6.1, HAtagged Kir6.2 or untagged Kv2.1 plasmid probed with N366/60 (left) or N52A/42 (right) TC supe. Right: adult rat brain membrane immunoblot Mouse IgG2a N366/60 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €460.00
  Antibodies Incorporated

KCNJ8 antibody

Left: immunoblot against extracts of COS cells transiently transfected with Myc-tagged Kir6.1, HAtagged Kir6.2 or untagged Kv2.1 plasmid probed with N366/60 (left) or N52A/42 (right) TC supe. Right: adult rat brain membrane immunoblot Mouse IgG2a N366/60 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €540.00
  Antibodies Incorporated

KCNJ8 (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue reacted with KCNJ8 Antibody (N-term) Cat.-No AP52312PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

KCNJ8 - human gene knockout kit via CRISPR

KCNJ8 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KCNJ8 - human gene knockout kit via CRISPR

KCNJ8 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCNJ8 - human gene knockout kit via CRISPR

KCNJ8 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCNJ8 - human gene knockout kit via CRISPR

KCNJ8 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KCNJ8 (mGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 8 (KCNJ8), 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNJ8 (mGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 8 (KCNJ8), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, KCNJ8 (Myc-DDK tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 8 (KCNJ8) , 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNJ8 (Myc-DDK tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 8 (KCNJ8) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcnj8 (GFP-tagged) - Mouse potassium inwardly-rectifying channel, subfamily J, member 8 (Kcnj8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnj8 (GFP-tagged) - Mouse potassium inwardly-rectifying channel, subfamily J, member 8 (Kcnj8), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcnj8 (Myc-DDK-tagged) - Mouse potassium inwardly-rectifying channel, subfamily J, member 8 (Kcnj8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnj8 (Myc-DDK-tagged) - Mouse potassium inwardly-rectifying channel, subfamily J, member 8 (Kcnj8), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcnj8 (GFP-tagged ORF) - Rat potassium inwardly-rectifying channel, subfamily J, member 8 (Kcnj8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnj8 (GFP-tagged ORF) - Rat potassium inwardly-rectifying channel, subfamily J, member 8 (Kcnj8), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcnj8 (Myc-DDK-tagged ORF) - Rat potassium inwardly-rectifying channel, subfamily J, member 8 (Kcnj8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnj8 (Myc-DDK-tagged ORF) - Rat potassium inwardly-rectifying channel, subfamily J, member 8 (Kcnj8), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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