KCNK1 antibody

Principal name

KCNK1 antibody

Alternative names for KCNK1 antibody

KCNK1, HOHO1, KCNO1, TWIK1, Potassium channel subfamily K member 1, Potassium channel KCNO1, Inward rectifying potassium channel protein TWIK-1

SwissProt ID

O00180 (Human), O08581 (Mouse), Q9Z2T2 (Rat)

Gene ID

3775 (KCNK1), 16525 (Kcnk1), 59324

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Ms (Mouse), Rb (Rabbit), African clawed frog

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of KCNK1 antibody

K2P1.1 (also med TWIK-1 or KCNK1) is a member of the 2-pore (2P) domain K+ channels family that at the moment includes 14 members. These channels show little time or voltage dependence and are considered to be â??leakâ? or â??backgroundâ? K+ channels, thereby generating background currents which help set the membrane resting potential and cell excitation. The K2P channels have a sigture topology that includes four transmembrane domains and two pore domains with intracellular N- and C termini. K2P channels are regulated by diverse physical and chemical stimuli including temperature, pH, mechanical stretch, inhalation anesthetics, etc. but are insensitive to the classical K+ channel blockers. K2P1.1 was the first of the K2P channels to be identified and as its origil me indicates (Tandem of P domains in a Weak Inward rectifier K+ channel) the channel behaves as a weak inward rectifier when expressed in heterologous systems. The channel is ubiquitously expressed with the most prominent expression in the brain, kidney and heart. We have now produced a novel antibody directed against a highly conserved epitope in the extracellular region of the human K2P1.1 channel. The antibody will also react with rat and mouse samples.

General readings

Feliciangeli, S., et al. J. Biol. Chem. 285(7):4798-4805(2010)
McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
Zhou, M., et al. J. Neurosci. 29(26):8551-8564(2009)
Goldstein, S.A., et al. Pharmacol. Rev. 57(4):527-540(2005)
Rajan, S., et al. Cell 121(1):37-47(2005)

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNK1 antibody

  Rabbit polyclonal anti-KCNK1 antibody  
Western blot analysis of extracts from Jurkat cells, using KCNK1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

KCNK1 antibody

  Rabbit Polyclonal Anti-K2P1.1 (TWIK-1) (extracellular)  
Western blot analysis of rat brain lysate: 1. Anti-K2P1.1 (TWIK-1) (extracellular) antibody, (1:200). 2. Anti-K2P1.1 (TWIK-1) (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNK1 antibody

  Rabbit Polyclonal Anti-KCNK1 Antibody  
Western blot analysis of KCNK1 in 3T3 cell lysate with KCNK1 antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNK1 antibody

  Rabbit Polyclonal Anti-KCNK1 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using (KCNK1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

KCNK1 antibody

Western blot (WB) analysis of TWIK-1 antibody (Cat.-no.: AP01494PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

KCNK1 (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with KCNK1 Antibody (C-term) Cat.-No AP52313PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

KCNK1 (C-term) antibody

Western blot analysis of KCNK1 Antibody (C-term) Cat.-No AP52314PU-N in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the KCNK1 antibody detected the KCNK1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

KCNK1 antibody

Western blot analysis of extracts from Jurkat cells, using KCNK1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, WB
50 µg / €230.00
  Assay Biotech

KCNK1 antibody

Western blot analysis of extracts from Jurkat cells, using KCNK1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KCNK1 (mGFP-tagged) - Human potassium channel, subfamily K, member 1 (KCNK1), 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNK1 (mGFP-tagged) - Human potassium channel, subfamily K, member 1 (KCNK1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, KCNK1 (Myc-DDK tagged) - Human potassium channel, subfamily K, member 1 (KCNK1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, KCNK1 (Myc-DDK tagged) - Human potassium channel, subfamily K, member 1 (KCNK1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcnk1 (GFP-tagged) - Mouse potassium channel, subfamily K, member 1 (Kcnk1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnk1 (GFP-tagged) - Mouse potassium channel, subfamily K, member 1 (Kcnk1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcnk1 (Myc-DDK-tagged) - Mouse potassium channel, subfamily K, member 1 (Kcnk1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnk1 (Myc-DDK-tagged) - Mouse potassium channel, subfamily K, member 1 (Kcnk1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcnk1 (GFP-tagged ORF) - Rat potassium channel, subfamily K, member 1 (Kcnk1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnk1 (GFP-tagged ORF) - Rat potassium channel, subfamily K, member 1 (Kcnk1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcnk1 (Myc-DDK-tagged ORF) - Rat potassium channel, subfamily K, member 1 (Kcnk1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnk1 (Myc-DDK-tagged ORF) - Rat potassium channel, subfamily K, member 1 (Kcnk1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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